# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2405393 | F | Induction of apoptosis in human CNE2Z cells assessed as expression of caspase-3 at 1 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis in presence of tamoxifen, NPPB, ClC-3 siRNA | Homo sapiens | 1 | ALA2401713 | cell-based format | Scientific Literature | |
2. | ALA2405394 | F | Induction of apoptosis in human CNE2Z cells assessed as induction of PARP cleavage at 1 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis in presence of tamoxifen, NPPB, ClC-3 siRNA | Homo sapiens | 1 | ALA2401713 | cell-based format | Scientific Literature | |
3. | ALA2405395 | F | Induction of apoptosis in human CNE2Z cells assessed as increase in apoptotic cell level at 1 to 10 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis in presence of tamoxifen, NPPB, ClC-3 siRNA | Homo sapiens | 1 | ALA2401713 | cell-based format | Scientific Literature | |
4. | ALA2405400 | F | Induction of apoptosis in human CNE2Z cells assessed as activation of caspase-8 at 1 to 50 uM after 24 hrs by luminometric analysis | Homo sapiens | 1 | ALA2401713 | cell-based format | Scientific Literature | |
5. | ALA2405401 | F | Induction of apoptosis in human CNE2Z cells assessed as activation of caspase-3/7 at 1 to 50 uM after 24 hrs by luminometric analysis | Homo sapiens | 1 | ALA2401713 | cell-based format | Scientific Literature | |
6. | ALA2405402 | F | Induction of apoptosis in human CNE2Z cells assessed as activation of caspase-3 at 1 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | ALA2401713 | cell-based format | Scientific Literature | |
7. | ALA2405403 | F | Induction of apoptosis in human CNE2Z cells assessed as induction of PARP cleavage at 1 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | ALA2401713 | cell-based format | Scientific Literature | |
8. | ALA2405404 | F | Induction of apoptosis in human CNE2Z cells assessed as increase in apoptotic cell level at 1 to 10 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 2 | ALA2401713 | cell-based format | Scientific Literature | |
9. | ALA4603916 | F | Antiproliferative activity against human CNE2Z cells assessed as growth inhibition after 72 hrs by MTT assay | Homo sapiens | 19 | ALA4602636 | cell-based format | Scientific Literature | |
10. | ALA4624409 | F | Antiproliferative activity against human CNE2Z cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 3 | ALA4622896 | cell-based format | Scientific Literature | |
11. | ALA4624420 | F | Antitumor activity against human CNE2Z cells xenografted in nude mouse assessed as reduction in tumor volume at 1 mg/kg, ip administered for 19 days relative to control | Homo sapiens | 1 | ALA4622896 | organism-based format | Scientific Literature |