# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1794443 | F | PUBCHEM_BIOASSAY: Mode of action assay-Specificity test for the KCNQ2 activators in the KCNQ5 expressing cells. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2239, AID2258, AID2287] | ⋯ | ALA1201862 | cell-based format | PubChem BioAssays | ||
2. | ALA2327422 | B | Positive modulatory activity at voltage-gated K channel 7.5 (unknown origin) | Homo sapiens | 1 | ALA2321869 | single protein format | Scientific Literature | |
3. | ALA4385384 | B | Activity at human KCNQ5 expressed in CHOK1 cells assessed as ratio of amplitude of outward current in presence of test compound to amplitude of outward current in absence of test compound at 10 uM at -10 mV by whole cell patch clamp assay | Homo sapiens | 28 | ALA4382285 | cell-based format | Scientific Literature | |
4. | ALA4385395 | B | Activity at human KCNQ5 expressed in CHOK1 cells assessed as ratio of amplitude of outward current in presence of test compound to amplitude of outward current in absence of test compound at 10 uM at +60 mV by whole cell patch clamp assay | Homo sapiens | 1 | ALA4382285 | cell-based format | Scientific Literature | |
5. | ALA4385397 | B | Agonist activity at human KCNQ5 expressed in CHOK1 cells by whole cell patch clamp assay | Homo sapiens | 4 | ALA4382285 | cell-based format | Scientific Literature | |
6. | ALA4403828 | A | Activation of human Kv7.5 expressed in CHO cells assessed as delta V at 10 uM by whole cell patch clamp electrophysiology assay | Homo sapiens | 3 | ALA4402547 | cell-based format | Scientific Literature | |
7. | ALA4403832 | A | Activation of human Kv7.5 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assay | Homo sapiens | 3 | ALA4402547 | cell-based format | Scientific Literature | |
8. | ALA5116584 | B | Agonist activity at Kv7.5 (unknown origin) expressed in CHO cells co-expressing GFP | Homo sapiens | 4 | ALA5113435 | cell-based format | Scientific Literature | |
9. | ALA5125932 | B | Agonist activity at human KCNQ5 channel expressed in CHO cells assessed as increase in outward current by patch clamp electrophysiology method | Homo sapiens | 1 | ALA5120947 | cell-based format | Scientific Literature | |
10. | ALA5151180 | B | Agonist activity at human KCNQ5 channel expressed in CHO cells assessed as shift of half voltage of maximal activation at 0.1 uM by patch clamp method | Homo sapiens | 1 | ALA5149984 | cell-based format | Scientific Literature | |
11. | ALA5151181 | B | Agonist activity at human KCNQ5 channel expressed in CHO cells assessed as amplitude change of outward current at 0.1 uM by patch clamp method | Homo sapiens | 1 | ALA5149984 | cell-based format | Scientific Literature | |
12. | ALA5151182 | B | Agonist activity at human KCNQ5 channel expressed in CHO cells assessed as shift of half voltage of maximal activation at 10 uM by patch clamp method | Homo sapiens | 1 | ALA5149984 | cell-based format | Scientific Literature | |
13. | ALA5151183 | B | Agonist activity at human KCNQ5 channel expressed in CHO cells assessed as amplitude change of outward current at 10 uM by patch clamp method | Homo sapiens | 1 | ALA5149984 | cell-based format | Scientific Literature |