# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4672064 | F | Inhibition of muscle contraction in Swiss mouse isolated phrenic nerve hemidiaphragm muscle preparation assessed as reduction of 0.1 Hz stimulation-induced isometric twitch force incubated for 20 to 25 mins | Mus musculus | 4 | ALA4665854 | tissue-based format | Scientific Literature | |
2. | ALA4672085 | F | Inhibition of muscle contraction in Swiss mouse isolated phrenic nerve hemidiaphragm muscle preparation assessed as reduction of 0.1 Hz stimulation-induced isometric twitch force by measuring time required to block 50% of nerve-evoked muscle contraction | Mus musculus | 1 | ALA4665854 | tissue-based format | Scientific Literature | |
3. | ALA4672086 | F | Inhibition of muscle contraction in Swiss mouse isolated phrenic nerve hemidiaphragm muscle preparation assessed as reduction of 0.1 Hz stimulation-induced isometric twitch force by measuring time required for 40% recovery of of nerve-evoked muscle contraction | Mus musculus | 1 | ALA4665854 | tissue-based format | Scientific Literature | |
4. | ALA4672087 | F | Inhibition of muscle contraction in Swiss mouse isolated phrenic nerve hemidiaphragm muscle preparation assessed as reduction of peak amplitude of 0.1 Hz stimulation-induced nerve contraction at 16 nM incubated for 30 mins relative to control | Mus musculus | 1 | ALA4665854 | tissue-based format | Scientific Literature | |
5. | ALA4672088 | F | Inhibition of muscle contraction in Swiss mouse isolated phrenic nerve hemidiaphragm muscle preparation assessed as reduction of peak amplitude of 0.1 Hz stimulation-induced nerve contraction at 16 nM incubated for 30 mins followed addition of 10 uM addition of 3,4-DAP for 27 mins by relative to control | Mus musculus | 1 | ALA4665854 | tissue-based format | Scientific Literature | |
6. | ALA4672089 | F | Inhibition of muscle contraction in Swiss mouse isolated phrenic nerve hemidiaphragm muscle preparation assessed as reduction of twitch tension-time integrals of 0.1 Hz stimulation-induced nerve contraction at 16 nM incubated for 30 mins followed addition of 10 uM addition of 3,4-DAP for 27 mins by relative to control | Mus musculus | 1 | ALA4665854 | tissue-based format | Scientific Literature | |
7. | ALA4672090 | F | Induction of fading of train-of four repetitive stimulation pattern in Swiss mouse isolated phrenic nerve hemidiaphragm muscle preparation measured at 76% neuromuscular block | Mus musculus | 1 | ALA4665854 | tissue-based format | Scientific Literature | |
8. | ALA4672091 | F | Reduction in fading of train-of four repetitive stimulation pattern in Swiss mouse isolated phrenic nerve hemidiaphragm muscle preparation at 20 nM | Mus musculus | 4 | ALA4665854 | tissue-based format | Scientific Literature |