| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2327055 | B | Agonist activity at rat TRPV4 | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 2. | ALA2327057 | B | Antagonist activity at rat TRPV4 | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 3. | ALA3227132 | B | Agonist activity at rat TRPV4 expressed in CHOK1 cells assessed as changes in intracellular calcium level measured for 5 mins by FLIPR assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA3227451 | B | Antagonist activity at rat TRPV4 expressed in CHOK1 cells assessed as inhibition of PF-04674114/GSK1016790A-induced changes in intracellular calcium level measured for 5 mins by FLIPR assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3383311 | B | Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3615487 | B | Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 mins | Rattus norvegicus | 19 | cell-based format | Scientific Literature | ||
| 7. | ALA3615623 | B | Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of 20% hypotonic solution-induced Ca2+ influx | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3615625 | B | Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-stimulated calcium flux after 10 mins | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3855634 | B | Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activation | Rattus norvegicus | 19 | single protein format | Scientific Literature | ||
| 10. | ALA3855668 | B | Antagonist activity at rat TRPV4 assessed as inhibition of hypotonicity-induced activation | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 11. | ALA3859462 | B | Antagonist activity at rat recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 300 nM 4alphaPDD-induced calcium mobilization by FLIPR assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3997707 | B | Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of GSK634775A-induced calcium influx preincubated for 10 mins followed by GSK634775A addition by Fura-4 dye based FLIPR assay | Rattus norvegicus | 30 | cell-based format | Scientific Literature | ||
| 13. | ALA3997755 | B | Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-induced current at holding potential of -40 mV by Whole cell patch-clamp method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3997758 | B | Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-induced intracellular calcium after 10 mins in presence of 45Ca2+ by microbeta liquid scintillation counting method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4050583 | B | Antagonist activity at recombinant rat TRPV4 expressed in CHOK1 cells assessed as inhibition of 4alphaPDD-induced activation pretreated for 5 mins followed by 4alphaPDD stimulation measured for 5 mins by FLIPR assay | Rattus norvegicus | 11 | cell-based format | Scientific Literature | ||
| 16. | ALA4143895 | B | Agonist activity at recombinant rat TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluorescence assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4235231 | B | Agonist activity at rat TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay relative to ionomycin | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 18. | ALA4235232 | B | Agonist activity at rat TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 19. | ALA4235233 | B | Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced increase in intracellular calcium level pretreated for 5 mins followed by GSK1016790A addition by Fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 20. | ALA4307492 | B | Inhibition of rat TRPV4 expressed in baculovirus infected HEK/MSR 2 cells pre-incubated for 10 mins followed by GSK634775A addition by Fura-2 dye based FLIPR assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature |
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