# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA617982 | B | Affinity at 5-hydroxytryptamine 3 receptor from rat frontal cortex using [3H]granisetron as radioligand (For granisetron = Ki(nM)=0.3+/-0.01) | 2 | ALA1134339 | tissue-based format | Scientific Literature | ||
2. | ALA617983 | B | Affinity at 5-hydroxytryptamine 3 receptor (For granisetron = Ki (nM)=0.3+/-0.01) | 1 | ALA1134339 | single protein format | Scientific Literature | ||
3. | ALA619647 | F | Compound was tested for its antagonistic activity against 5-hydroxytryptamine 3 receptor in rat brain using [3H]zacopride as the radioligand. | 1 | ALA1129720 | tissue-based format | Scientific Literature | ||
4. | ALA619648 | F | Compound was tested in vitro for its antagonistic activity against 5-hydroxytryptamine 3 receptor | 1 | ALA1129720 | assay format | Scientific Literature | ||
5. | ALA619165 | F | Compound was tested in vitro for its antagonistic activity against 5-hydroxytryptamine 3 receptor in rat CNS. | 1 | ALA1129720 | assay format | Scientific Literature | ||
6. | ALA620719 | F | Compound was evaluated in vivo for the antagonistic activity towards 5-hydroxytryptamine 3 receptor | 6 | ALA1126380 | organism-based format | Scientific Literature | ||
7. | ALA872924 | B | Compound was tested for its binding affinity towards 5-HT-3 receptor in whole rat brain using (S)-[125I]-zacopride as the radioligand. | 1 | ALA1129720 | assay format | Scientific Literature | ||
8. | ALA620720 | B | Compound was tested for its binding affinity towards 5-hydroxytryptamine 3 receptor | 1 | ALA1129720 | single protein format | Scientific Literature | ||
9. | ALA620721 | B | Compound was tested for its binding affinity towards 5-hydroxytryptamine 3 receptor in whole rat brain using (S)-[125I]-zacopride as the radioligand. | 1 | ALA1129720 | assay format | Scientific Literature | ||
10. | ALA620722 | B | Compound was tested for its binding affinity towards 5-hydroxytryptamine 3 receptor in whole rat brain using [125I]DAIZAC as the radioligand. | 2 | ALA1129720 | assay format | Scientific Literature | ||
11. | ALA620724 | B | In Vitro Binding affinity againist 5-hydroxytryptamine 3 receptor by displacing [3H]-Q-ICS 205-930 from rat cortex homogenates | 3 | ALA1127719 | assay format | Scientific Literature | ||
12. | ALA620726 | F | Antagonist activity (100 ug/kg) for the Bezold Jarisch reflex evoked by 30 (ug/Kg) of 5-hydroxytryptamine 3 receptor in ethylurethane anesthetized rats i.v. | Rattus norvegicus | 1 | ALA1130427 | assay format | Scientific Literature | |
13. | ALA619059 | F | Response at rat 5-hydroxytryptamine 3a receptor expressed in xenopus oocytes | Rattus norvegicus | 1 | ALA1147510 | cell-based format | Scientific Literature | |
14. | ALA619060 | F | Ability to block serotonin (30 uM)-evoked responses at rat 5HT3-alpha receptor expressed in xenopus oocytes | Rattus norvegicus | 1 | ALA1147510 | cell-based format | Scientific Literature | |
15. | ALA875095 | F | Effect on rat 5-hydroxytryptamine 3a receptor expressed in xenopus oocytes at concentration up to 100 uM | Rattus norvegicus | 1 | ALA1147510 | cell-based format | Scientific Literature | |
16. | ALA839978 | B | In vitro inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptor in rat cerebral cortex membranes | Rattus norvegicus | 1 | ALA1143573 | cell membrane format | Scientific Literature | |
17. | ALA915252 | B | Displacement of [3H]LY278584 from rat cortex 5HT3 receptor | Rattus norvegicus | 1 | ALA1142963 | assay format | Scientific Literature | |
18. | ALA932565 | B | Binding affinity to rat 5HT3 receptor | Rattus norvegicus | 2 | ALA1145564 | single protein format | Scientific Literature | |
19. | ALA1006686 | B | Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate | Rattus norvegicus | 19 | ALA1136924 | assay format | Scientific Literature | |
20. | ALA997997 | B | Displacement of [3H]zacopride from 5HT3 receptor in rat cortex | Rattus norvegicus | 3 | ALA1136924 | assay format | Scientific Literature |