| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4702076 | B | Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation by measuring ratio of PARP1 to beta tubulin protein level at 1 nM incubated for 24 hrs by Western blot analysis (Rvb = 100 No_unit) | Homo sapiens | 14 | ALA4699498 | cell-based format | Scientific Literature | |
| 2. | ALA4702079 | B | Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation at 1 to 1000 nM incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4699498 | cell-based format | Scientific Literature | |
| 3. | ALA4702080 | B | Protac activity at CRBN/PARP1 in human Capan1 cells assessed as induction of PARP1 degradation at 1 to 1000 nM incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4699498 | cell-based format | Scientific Literature | |
| 4. | ALA4702081 | B | Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation at 10 nM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 2 | ALA4699498 | cell-based format | Scientific Literature | |
| 5. | ALA4702082 | B | Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation at 100 nM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4699498 | cell-based format | Scientific Literature | |
| 6. | ALA4702083 | B | Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation at 1 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4699498 | cell-based format | Scientific Literature | |
| 7. | ALA4702084 | B | Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation by measuring ratio of PARP1 to beta tubulin protein level at 10 nM incubated for 24 hrs by Western blot analysis (Rvb = 100 No_unit) | Homo sapiens | 14 | ALA4699498 | cell-based format | Scientific Literature | |
| 8. | ALA4702085 | B | Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation by measuring ratio of PARP1 to beta tubulin protein level at 100 nM incubated for 24 hrs by Western blot analysis (Rvb = 100 No_unit) | Homo sapiens | 14 | ALA4699498 | cell-based format | Scientific Literature | |
| 9. | ALA4702086 | B | Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation by measuring ratio of PARP1 to beta tubulin protein level at 1000 nM incubated for 24 hrs by Western blot analysis (Rvb = 100 No_unit) | Homo sapiens | 14 | ALA4699498 | cell-based format | Scientific Literature | |
| 10. | ALA4702087 | B | Protac activity at CRBN/PARP1 in human CAPAN-1 cells assessed as induction of PARP1 degradation by measuring ratio of PARP1 to beta tubulin protein level at 1 nM incubated for 24 hrs by Western blot analysis (Rvb = 100 No_unit) | Homo sapiens | 14 | ALA4699498 | cell-based format | Scientific Literature | |
| 11. | ALA4702088 | B | Protac activity at CRBN/PARP1 in human CAPAN-1 cells assessed as induction of PARP1 degradation by measuring ratio of PARP1 to beta tubulin protein level at 10 nM incubated for 24 hrs by Western blot analysis (Rvb = 100 No_unit) | Homo sapiens | 14 | ALA4699498 | cell-based format | Scientific Literature | |
| 12. | ALA4702089 | B | Protac activity at CRBN/PARP1 in human CAPAN-1 cells assessed as induction of PARP1 degradation by measuring ratio of PARP1 to beta tubulin protein level at 100 nM incubated for 24 hrs by Western blot analysis (Rvb = 100 No_unit) | Homo sapiens | 14 | ALA4699498 | cell-based format | Scientific Literature | |
| 13. | ALA4702090 | B | Protac activity at CRBN/PARP1 in human CAPAN-1 cells assessed as induction of PARP1 degradation by measuring ratio of PARP1 to beta tubulin protein level at 1000 nM incubated for 24 hrs by Western blot analysis (Rvb = 100 No_unit) | Homo sapiens | 14 | ALA4699498 | cell-based format | Scientific Literature | |
| 14. | ALA4702098 | B | Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4699498 | cell-based format | Scientific Literature | |
| 15. | ALA4702099 | B | Protac activity at CRBN/PARP1 in human CAPAN-1 cells assessed as induction of PARP1 degradation incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4699498 | cell-based format | Scientific Literature | |
| 16. | ALA4702100 | B | Protac activity at CRBN/PARP1 in human SW-620 cells assessed as induction of PARP1 degradation incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4699498 | cell-based format | Scientific Literature | |
| 17. | ALA4702101 | B | Protac activity at CRBN/PARP1 in human CAPAN-1 cells assessed as induction of PARP1 degradation at 100 nM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4699498 | cell-based format | Scientific Literature | |
| 18. | ALA4702102 | B | Protac activity at CRBN/PARP1 in human SW-620 cells assessed as induction of PARP1 degradation at 10 nM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4699498 | cell-based format | Scientific Literature | |
| 19. | ALA4702103 | B | Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation at 30 nM measured within 1 hr by Western blot analysis | Homo sapiens | 1 | ALA4699498 | cell-based format | Scientific Literature | |
| 20. | ALA4702104 | B | Protac activity at CRBN/PARP1 in human MDA-MB-436 cells assessed as induction of PARP1 degradation at 10 nM measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA4699498 | cell-based format | Scientific Literature |
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