#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4729440	B	Protac activity at CRBN/IRAK3 in LPS-induced human THP1 cells assessed as induction of IRAK3 degradation at 1 uM by Western blot analysis relative to control	Homo sapiens	8		tissue-based format	Scientific Literature
2.	ALA4729457	B	Protac activity at CRBN/IRAK3 in LPS-induced human THP1 cells assessed as induction of IRAK3 degradation at 10 uM by Western blot analysis relative to control	Homo sapiens	8		tissue-based format	Scientific Literature
3.	ALA4729459	B	Protac activity at CRBN/IRAK3 in LPS-induced human THP1 cells assessed as induction of IRAK3 degradation after 16 hrs by Western blot analysis	Homo sapiens	3		tissue-based format	Scientific Literature
4.	ALA4729460	B	Protac activity at CRBN/IRAK3 in LPS-induced human THP1 cells assessed as induction of IRAK3 degradation after 16 hrs by Western blot analysis relative to control	Homo sapiens	2		tissue-based format	Scientific Literature
5.	ALA4729476	B	Protac activity at CRBN/IRAK3 in LPS-induced human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM measured after 6 hrs by HPLC-MS based global proteomic analysis relative to control	Homo sapiens	1		tissue-based format	Scientific Literature
6.	ALA4729483	B	Protac activity at CRBN/IRAK3 in human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM measured after 24 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
7.	ALA4729484	B	Protac activity at CRBN/IRAK3 in human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM measured after 2 to 72 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
8.	ALA4729485	B	Protac activity at CRBN/IRAK3 in human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM preincubated for 16 hrs followed by compound washout and measured after 24 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
9.	ALA4729486	B	Protac activity at CRBN/IRAK3 in human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM measured after 6 hrs in presence of proteasome inhibitor MG132 by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
10.	ALA4729487	B	Protac activity at CRBN/IRAK3 in human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM measured after 6 hrs in presence of NEDD8-activating enzyme inhibitor MLN4924 by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
11.	ALA4729488	B	Protac activity at CRBN/IRAK3 in human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM measured after 6 hrs in presence of IRAK3 ligand cis-1-(4-(4-((5-Isopropylpyrrolo[2,1-f][1,2,4]triazin-4-yl)amino)-cyclohexyl)piperazin-1-yl)ethanone by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
12.	ALA4729489	B	Protac activity at CRBN/IRAK3 in human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM measured after 6 hrs in presence of 10 uM thalidomide by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
13.	ALA4729490	B	Protac activity at CRBN/IRAK3 in human THP1 cells assessed as induction of IRAK3 degradation at 0.1 to 10 uM measured after 24 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
14.	ALA4729491	B	Protac activity at CRBN/IRAK3 in human PBMC derived primary macrophages assessed as induction of IRAK3 degradation at 0.3 uM measured after 8 to 32 hrs by Western blot analysis	Homo sapiens	2		tissue-based format	Scientific Literature
15.	ALA4729492	B	Protac activity at CRBN/IRAK3 in human PBMC derived primary macrophages assessed as induction of IRAK3 degradation at 0.3 uM preincubated for 8 hrs followed by LPS-stimulation and measured after 8 to 32 hrs by Western blot analysis	Homo sapiens	2		tissue-based format	Scientific Literature