# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4685764 | B | Protac activity at VHL/BCL2 in human MOLT-4 cells assessed as induction of BCL2 degradation at 100 nM measured after 16 hrs by immunoblotting analysis | Homo sapiens | 25 | ALA4680217 | cell-based format | Scientific Literature | |
2. | ALA5054293 | B | Binding affinity to Halo-tagged VHL/HiBiT-tagged BCL-2 (unknown origin) expressed in HEK293T cells assessed as ternary complex formation at up to 100000 nM measured after 6 hrs by NanoBRET assay | Homo sapiens | 5 | ALA5053511 | cell-based format | Scientific Literature | |
3. | ALA5054296 | B | Binding affinity to VHL/BCL-2 in human RS4-11 cells assessed as ternary complex formation at up to 300 nM measured after 12 hrs by immunoprecipitation assay | Homo sapiens | 4 | ALA5053511 | cell-based format | Scientific Literature | |
4. | ALA5054298 | B | Binding affinity to VHL/BCL-2 in human RS4-11 cells assessed as ternary complex formation at up to 300 nM measured after 12 hrs in presence of VHL-032 by immunoprecipitation assay | Homo sapiens | 4 | ALA5053511 | cell-based format | Scientific Literature |