| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4726617 | B | Protac activity at VHL/AhR in human MCF7 cells assessed as induction of AhR protein degradation by measuring AhR protein level at 5 uM incubated for 8 hrs by western blot analysis relative to lamin B | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4726618 | B | Protac activity at VHL/AhR in human MCF7 cells assessed as induction of AhR protein degradation by measuring AhR protein level at 10 uM incubated for 8 hrs by western blot analysis relative to lamin B | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4726619 | B | Protac activity at VHL/AhR in human MCF7 cells assessed as induction of AhR protein degradation by measuring AhR protein level at 20 uM incubated for 8 hrs by western blot analysis relative to lamin B | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4726626 | B | Protac activity at VHL/AhR in human MCF7 cells assessed as induction of AhR protein degradation by measuring AhR protein level at 5 uM incubated for 24 hrs by western blot analysis relative to lamin B | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4726627 | B | Protac activity at VHL/AhR in human MCF7 cells assessed as induction of AhR protein degradation by measuring AhR protein level at 10 uM incubated for 24 hrs by western blot analysis relative to lamin B | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4726628 | B | Protac activity at VHL/AhR in human MCF7 cells assessed as induction of AhR protein degradation by measuring AhR protein level at 20 uM incubated for 24 hrs by western blot analysis relative to lamin B | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4726645 | B | Protac activity at VHL/AhR in human MCF7 cells assessed as induction of AhR protein degradation by measuring AhR protein level at 20 uM incubated for 8 hrs in presence of proteasome inhibitor, MG132 by western blot analysis relative to lamin B | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4726648 | B | Protac activity at VHL/AhR in human MCF7 cells assessed as induction of AhR protein degradation by measuring AhR protein level at 20 uM incubated for 8 hrs in presence of ubiquitin activating inhibitor MLN7243 by western blot analysis relative to lamin B | Homo sapiens | 1 | cell-based format | Scientific Literature |
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