# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4730721 | Binding | Protac activity at CRBN/FAK in mouse TM3 cells assessed as reduction in FAK autophosphorylation at tyr 397 residue at <1 nM after 8 hrs by Western blot analysis | Mus musculus | 1 | ALA4725428 | cell-based format | Scientific Literature | |
2. | ALA4730729 | Binding | Protac activity at CRBN/FAK in mouse TM3 cells assessed as induction of FAK degradation after 8 hrs by Western blot analysis | Mus musculus | 1 | ALA4725428 | cell-based format | Scientific Literature | |
3. | ALA4730734 | Binding | Protac activity at CRBN/FAK in mouse TM3 cells assessed as reduction in FAK autophosphorylation at tyr 397 residue at 100 nM after 1 hr by Western blot analysis relative to control | Mus musculus | 1 | ALA4725428 | cell-based format | Scientific Literature | |
4. | ALA4730735 | Binding | Protac activity at CRBN/FAK in mouse TM3 cells assessed as reduction in FAK autophosphorylation at tyr 397 residue at 3 uM after 8 hrs by Western blot analysis | Mus musculus | 1 | ALA4725428 | cell-based format | Scientific Literature | |
5. | ALA4730736 | Binding | Protac activity at CRBN/FAK in mouse TM3 cells assessed as reduction in FAK autophosphorylation at tyr 397 residue at 1 to 3000 nM after 8 hrs by Western blot analysis | Mus musculus | 1 | ALA4725428 | cell-based format | Scientific Literature |