# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3430273 | Binding | Inhibition of MRP1 in human A2780adr cells at 10 uM pre-incubated for 30 mins followed by calcein AM addition and further incubated for 60 mins by calcein AM assay | Homo sapiens | 22 | ALA3425464 | cell-based format | Scientific Literature | |
2. | ALA3537697 | ADME | Activity of recombinant human ABCC1 expressed in baculovirus infected insect Sf21 cell plasma membrane vesicles assessed as transporter-mediated drug uptake at 10 uM by liquid scintillation counting analysis in presence of ATP | Homo sapiens | 1 | ALA3526024 | cell-based format | Scientific Literature | |
3. | ALA3537700 | ADME | Activity of recombinant human ABCC1 expressed in baculovirus infected insect Sf21 cell plasma membrane vesicles assessed as transporter-mediated drug uptake by liquid scintillation counting analysis in presence of ATP | Homo sapiens | 1 | ALA3526024 | cell-based format | Scientific Literature | |
4. | ALA3537703 | ADME | Activity of recombinant human ABCC1 expressed in baculovirus infected insect Sf21 cell plasma membrane vesicles assessed as transporter-mediated drug uptake per mg of protein by liquid scintillation counting analysis in presence of ATP | Homo sapiens | 1 | ALA3526024 | cell-based format | Scientific Literature | |
5. | ALA3533749 | ADME | Drug uptake assessed as human MRP1-mediated drug transport using inside-out membrane vesicles by measuring +ATP/-ATP ratio by LC-MS/MS analysis | Homo sapiens | 2 | ALA3526031 | assay format | Scientific Literature | |
6. | ALA3533480 | ADME | Inhibition of MRP1-mediated E2-17betaG transport in human MRP1 expressing HEK293 cells at 33 uM during 5 min | Homo sapiens | 1 | ALA3526013 | cell-based format | Scientific Literature | |
7. | ALA3533486 | ADME | Inhibition of MRP1-mediated E2-17betaG transport in human MRP1 expressing HEK293 cells at 7 uM during 5 mins | Homo sapiens | 2 | ALA3526013 | cell-based format | Scientific Literature | |
8. | ALA3533487 | ADME | Inhibition of MRP1-mediated E2-17betaG transport in human MRP1 expressing HEK293 cells at 12 uM during 5 mins | Homo sapiens | 2 | ALA3526013 | cell-based format | Scientific Literature | |
9. | ALA3533488 | ADME | Inhibition of MRP1-mediated E2-17betaG transport in human MRP1 expressing HEK293 cells at 1 to 3 uM during 5 mins | Homo sapiens | 4 | ALA3526013 | cell-based format | Scientific Literature | |
10. | ALA3533489 | ADME | Inhibition of MRP1-mediated E2-17betaG transport in human MRP1 expressing HEK293 cells at 4 uM during 5 mins | Homo sapiens | 1 | ALA3526013 | cell-based format | Scientific Literature | |
11. | ALA3533494 | ADME | Inhibition of MRP1-mediated E2-17betaG transport in human MRP1 expressing HEK293 cells in presence of 0.6 to 5 uM E2-17betaG | Homo sapiens | 3 | ALA3526013 | cell-based format | Scientific Literature | |
12. | ALA3533496 | ADME | Noncompetitive inhibition of MRP1-mediated E2-17betaG transport in human MRP1 expressing HEK293 cells by Dixon plot | Homo sapiens | 2 | ALA3526013 | cell-based format | Scientific Literature | |
13. | ALA3533966 | ADME | Activity at MRP1 (unknown origin) expressed in baculovirus-infected HEK293 cells assessed as drug transport at 400 uM after 10 mins by reversed-phase HPLC analysis in presence of AMP | Homo sapiens | 1 | ALA3526030 | cell-based format | Scientific Literature | |
14. | ALA3536906 | ADME | Inhibition of human MRP1-mediated estradiol-17beta-D-glucuronide formation using inside-out membrane vesicles by LC-MS/MS analysis | Homo sapiens | 2 | ALA3526031 | assay format | Scientific Literature | |
15. | ALA3530756 | ADME | Activity at MRP1 (unknown origin) expressed in baculovirus-infected HEK293 cells assessed as drug transport at 400 uM after 10 mins by reversed-phase HPLC analysis in presence of ATP | Homo sapiens | 2 | ALA3526030 | cell-based format | Scientific Literature | |
16. | ALA3530762 | ADME | Activity at MRP1 (unknown origin) expressed in baculovirus-infected HEK293 cells assessed as drug transport at 400 uM after 10 mins by reversed phase-HPLC analysis in presence of GSH | Homo sapiens | 2 | ALA3526030 | cell-based format | Scientific Literature | |
17. | ALA3584583 | Binding | Modulation of MRP1 (unknown origin) transfected in human 2008/MRP1 cells assessed as potentiation of doxorubicin-induced cytotoxicity measured as doxorubicin IC50 at 1 uM after 5 days by MTS assay | Homo sapiens | 6 | ALA3580553 | cell-based format | Scientific Literature | |
18. | ALA3584584 | Binding | Modulation of MRP1 (unknown origin) transfected in human 2008/MRP1 cells assessed as potentiation of doxorubicin-induced cytotoxicity measured as doxorubicin IC50 at 1 uM after 5 days by MTS assay relative to doxorubicin alone treated cell | Homo sapiens | 6 | ALA3580553 | cell-based format | Scientific Literature | |
19. | ALA3614444 | Binding | Inhibition of MRP1 (unknown origin)-mediated calcein-AM efflux expressed in HEK293/MRP1 cells at 0.5 uM after 1 hr by flow cytometry | Homo sapiens | 24 | ALA3611986 | cell-based format | Scientific Literature | |
20. | ALA3767953 | Binding | Inhibition of human MRP1 transfected in MDCK2 cells assessed as inhibition of calcein-AM efflux | Homo sapiens | 33 | ALA3763047 | cell-based format | Scientific Literature |