# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4831179 | Functional | Induction of CDK9 degradation in tumor of human MDA-MB-231 cells xenografted in BALB/c mouse model at 0.15 mM intratumoral injection measured after 16 hrs by Western blot analysis relative to control | Homo sapiens | 2 | ALA4828763 | tissue-based format | Scientific Literature | |
2. | ALA4831180 | Functional | Induction of CDK7 degradation in tumor of human MDA-MB-231 cells xenografted in BALB/c mouse model at 0.15 mM intratumoral injection measured after 16 hrs by Western blot analysis relative to control | Homo sapiens | 2 | ALA4828763 | tissue-based format | Scientific Literature | |
3. | ALA4831187 | Functional | Effect on CDK7 protein level in tumor of BALB/c mouse xenografted with human MDA-MB-231 cells at 2.5 to 5 mg/kg, intratumoral injection daily for 7 days by Western blot analysis relative to control | Homo sapiens | 1 | ALA4828763 | organism-based format | Scientific Literature | |
4. | ALA4831188 | Functional | Reduction in CDK9 protein level in tumor of BALB/c mouse xenografted with human MDA-MB-231 cells at 2.5 mg/kg, intratumoral injection daily for 7 days by immunohistochemistry staining analysis relative to control | Homo sapiens | 1 | ALA4828763 | organism-based format | Scientific Literature | |
5. | ALA4831189 | Functional | Reduction in CDK9 protein level in tumor of BALB/c mouse xenografted with human MDA-MB-231 cells at 5 mg/kg, intratumoral injection daily for 7 days by immunohistochemistry staining analysis relative to control | Homo sapiens | 1 | ALA4828763 | organism-based format | Scientific Literature | |
6. | ALA4831190 | Functional | Reduction in MYC protein level in tumor of BALB/c mouse xenografted with human MDA-MB-231 cells at 2.5 mg/kg, intratumoral injection daily for 7 days by immunohistochemistry staining analysis relative to control | Homo sapiens | 1 | ALA4828763 | organism-based format | Scientific Literature | |
7. | ALA4831191 | Functional | Reduction in MYC protein level in tumor of BALB/c mouse xenografted with human MDA-MB-231 cells at 5 mg/kg, intratumoral injection daily for 7 days by immunohistochemistry staining analysis relative to control | Homo sapiens | 1 | ALA4828763 | organism-based format | Scientific Literature | |
8. | ALA4831192 | Functional | Reduction in CDK7 protein level in tumor of BALB/c mouse xenografted with human MDA-MB-231 cells at 2.5 mg/kg, intratumoral injection daily for 7 days by immunohistochemistry staining analysis relative to control | Homo sapiens | 1 | ALA4828763 | organism-based format | Scientific Literature | |
9. | ALA4831193 | Functional | Reduction in CDK7 protein level in tumor of BALB/c mouse xenografted with human MDA-MB-231 cells at 5 mg/kg, intratumoral injection daily for 7 days by immunohistochemistry staining analysis relative to control | Homo sapiens | 1 | ALA4828763 | organism-based format | Scientific Literature | |
10. | ALA4831194 | Functional | Reduction in Ki-67 protein level in tumor of BALB/c mouse xenografted with human MDA-MB-231 cells at 2.5 mg/kg, intratumoral injection daily for 7 days by immunohistochemistry staining analysis relative to control | Homo sapiens | 1 | ALA4828763 | organism-based format | Scientific Literature | |
11. | ALA4831195 | Functional | Reduction in Ki-67 protein level in tumor of BALB/c mouse xenografted with human MDA-MB-231 cells at 5 mg/kg, intratumoral injection daily for 7 days by immunohistochemistry staining analysis relative to control | Homo sapiens | 1 | ALA4828763 | organism-based format | Scientific Literature |