# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5252381 | B | Inhibition of Usher-1 syndrome artificial pR3X plasmid DNA construct assessed as suppression of premature termination codon and measured after 90 mins by Dual luciferase readthrough assay | 5 | nucleic acid format | Scientific Literature | |||
2. | ALA5252382 | B | Inhibition of Cystic Fibrosis artificial pG542X plasmid DNA construct assessed as suppression of premature termination codon and measured after 90 mins by Dual luciferase readthrough assay | 2 | nucleic acid format | Scientific Literature | |||
3. | ALA5252383 | B | Inhibition of Cystic Fibrosis artificial pW1282X plasmid DNA construct assessed as suppression of premature termination codon and measured after 90 mins by Dual luciferase readthrough assay | 2 | nucleic acid format | Scientific Literature | |||
4. | ALA4833441 | B | Induction of read through activity at TP53 R213X mutant premature termination codon in human DMS-114 cells assessed as expression of full length p53 levels at 62 ug/ml measured after 48 hrs by capillary electrophoresis western analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA4833444 | B | Induction of read through activity at TP53 R213X mutant premature termination codon in human DMS-114 cells assessed as increase in production of full length p53 at 125 ug/ml measured after 48 hrs by capillary electrophoresis western analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4833445 | B | Induction of read through activity at TP53 R213X mutant premature termination codon in human DMS-114 cells assessed as increase in production of full length p53 at 500 ug/ml measured after 48 hrs by capillary electrophoresis western analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4833446 | B | Induction of read through activity at TP53 R213X mutant premature termination codon in human DMS-114 cells assessed as increase in production of full length p53 at up to 500 ug/ml measured after 48 hrs by capillary electrophoresis western analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA4833448 | B | Induction of read through activity at TP53 R213X mutant premature termination codon in human DMS-114 cells assessed as increase in production of full length p53 at 31 to 250 ug/ml measured after 48 hrs by capillary electrophoresis western analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA5216864 | B | Induction of read through activity at T-p53 R213X mutant premature termination codon in human HDQ-P1 cells assessed as increase in production of full length p53 protein by MSD assay | Homo sapiens | 90 | cell-based format | Scientific Literature |