| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4840901 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as inhibition of G protein expression measured after 72 hrs by RT-qPCR method | Infectious hematopoietic necrosis virus | 4 | organism-based format | Scientific Literature | ||
| 2. | ALA4840902 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as inhibition of nucleoprotein gene expression at 0.1 to 100 uM measured after 72 hrs by RT-qPCR method relative to control | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA4840903 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as inhibition of phospho protein gene expression at 0.1 to 100 uM measured after 72 hrs by RT-qPCR method relative to control | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA4840904 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as inhibition of matrix protein gene expression at 0.1 to 100 uM measured after 72 hrs by RT-qPCR method relative to control | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA4840905 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as inhibition of polymerase protein gene expression at 0.1 to 100 uM measured after 72 hrs by RT-qPCR method relative to control | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA4840906 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as reduction of virus titre values at 0.25 to 25 uM measured after 72 to 96 hrs | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA4840907 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as suppression of virus-induced cytopathic effect at 100 uM | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4840908 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as decrease in virus-induced apoptosis by measuring early apoptotic cells measured after 72 hrs by Annexin V/PI staining based flowcytometry method (Rvb = 3.8%) | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4840909 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as decrease in virus-induced apoptosis by measuring viable cells measured after 72 hrs by Annexin V/PI staining based flowcytometry method (Rvb = 94%) | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4840910 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as decrease in virus-induced apoptosis by measuring formation of few apoptotic bodies in cells at 100 uM measured after 72 hrs by Flowcytometry assay | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4840911 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as decrease in virus-induced apoptosis by measuring appearance of normal sized nuclei in cells at 100 uM measured after 72 hrs by Flowcytometry assay | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4840916 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells at 25 uM preincubated for 1 to 4 hrs followed by compound washout and infected to EPC cells and measured after 72 hrs by RT-qPCR assay | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4840917 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as inhibition of virus-cell recognition at 25 uM measured after 30 mins by RT-qPCR method | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4840918 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as decrease in virus-induced apoptosis by measuring late apoptotic cells measured after 72 hrs by Annexin V/PI staining based flowcytometry method (Rvb = 1.95%) | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4840919 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as decrease in virus-induced apoptosis by measuring necrotic cells measured after 72 hrs by Annexin V/PI staining based flowcytometry method (Rvb = 0.29%) | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4840924 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as decrease in virus-induced apoptosis by measuring changes in cell morphology at 10 uM measured by ultrastructural analysis | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4840925 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as decrease in virus-induced apoptosis by measuring caspase-3 activity at 25 uM measured after 72 hrs by Caspase activity assay relative to control | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4840926 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as decrease in virus-induced apoptosis by measuring caspase-8 activity at 25 uM measured after 72 hrs by Caspase activity assay relative to control | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4840927 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Fathead minnow EPC cells assessed as decrease in virus-induced apoptosis by measuring caspase-9 activity at 25 uM measured after 72 hrs by Caspase activity assay relative to control | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4840928 | F | Antiviral activity against Infectious hematopoietic necrosis virus infected in Rainbow trout fish assessed as decrease of mortality rate ip measured after 4 days | Infectious hematopoietic necrosis virus | 1 | organism-based format | Scientific Literature |
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