| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA873946 | B | Inhibition of Mixed lineage kinase 1 (MLK1) | 11 | single protein format | Scientific Literature | |||
| 2. | ALA911978 | B | Inhibition of GST-MLK1 expressed in baculovirus | Homo sapiens | 28 | assay format | Scientific Literature | ||
| 3. | ALA911985 | F | Inhibition of MKK4 phosphorylation in MLK1 transfected CHO cells at 1 uM after 1 hr | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA911996 | F | Inhibition of MKK4 phosphorylation in MLK1 transfected CHO cells after 1 hr | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA941781 | B | Inhibition of MLK1 | 1 | single protein format | Scientific Literature | |||
| 6. | ALA921999 | B | Activity of human MLK1 kinase at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA974423 | B | Inhibition of MLK1 at 1 uM | 1 | single protein format | Scientific Literature | |||
| 8. | ALA1003945 | B | Inhibition of GST-fused human MLK1 | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 9. | ALA1003947 | B | Inhibition of GST-fused human MLK1 at 1 uM | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 10. | ALA1000436 | B | Inhibition of GST-fused human MLK1 expressed in CHO cells assessed as MKK4 phosphorylation | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 11. | ALA975449 | B | Inhibition of human MLK1 kinase assessed as residual enzyme activity at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA987195 | B | Inhibition of MLK1 at 3 uM | 1 | single protein format | Scientific Literature | |||
| 13. | ALA963873 | B | Binding affinity to MAP3K9 | 4 | single protein format | Scientific Literature | |||
| 14. | ALA1057483 | B | Inhibition of MLK1 at 1 uM | 1 | single protein format | Scientific Literature | |||
| 15. | ALA1063716 | B | Binding constant for MLK1 kinase domain | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 16. | ALA1057659 | B | Inhibition of MLK1 assessed as remaining enzyme activity at 3 uM relative to DMSO | 1 | single protein format | Scientific Literature | |||
| 17. | ALA1049950 | B | Inhibition of MLK1 assessed as remaining enzyme activity at 1 uM relative to DMSO | 1 | single protein format | Scientific Literature | |||
| 18. | ALA1047455 | B | Inhibition of MLK1 assessed as enzyme activity at 1 uM relative to untreated control | 1 | single protein format | Scientific Literature | |||
| 19. | ALA1045289 | B | Inhibition of MLK1 at 3 uM | 1 | single protein format | Scientific Literature | |||
| 20. | ALA1037976 | B | Binding affinity to human MLK1 at 200 nM by cell-based competition binding assay relative to control in presence of DTT | Homo sapiens | 1 | cell-based format | Scientific Literature |
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