# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4839371 | B | Inhibition of ATR in human HT29 cells assessed as reduction in gammaH2AX phosphorylation incubated for 30 mins by fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
2. | ALA5131990 | B | Binding affinity to ATR (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA5159408 | F | In vivo inhibition of ATR in human LoVo cells xenografted in NOD/SCID mouse assessed as inhibition of ATR phosphorylation at 50 to 100 mg/kg, po administered twice a day for 30 days by Western blot analysis | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
4. | ALA5159470 | F | In vivo inhibition of ATR in human LoVo cells xenografted in NOD/SCID mouse assessed as inhibition of Chk1 phosphorylation at 50 to 100 mg/kg, po administered twice a day for 30 days by Western blot analysis | Homo sapiens | 1 | organism-based format | Scientific Literature |