# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4823673 | B | Protac activity at SHP2/CRBN in human MV4-11 cells assessed as SHP2 degradation at 8 nM measured after 12 hrs by Western blot analysis relative to control | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
2. | ALA4823674 | B | Protac activity at SHP2/CRBN in human MV4-11 cells assessed as SHP2 degradation at 200 nM measured after 12 hrs by Western blot analysis relative to control | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
3. | ALA4823675 | B | Protac activity at SHP2/CRBN in human MV4-11 cells assessed as decrease in SHP2 protein level measured after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4823676 | B | Protac activity at SHP2/CRBN in human MV4-11 cells assessed as induction of SHP2 degradation measured after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4823677 | B | Protac activity at SHP2/CRBN in human MV4-11 cells assessed as SHP2 degradation at 100 nM measured after 6 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4823678 | B | Protac activity at SHP2/CRBN in human MV4-11 cells assessed as SHP2 degradation at 100 nM measured after 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |