| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4836911 | B | Disruption of interaction between human recombinant GST-tagged MKK3/VF-tagged MYC expressed in HEK293T cells measured after 2 hrs by TR-FRET assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4836912 | B | Disruption of interaction between human recombinant GST-tagged MKK3 (1 to 210 residues)/VF-tagged MYC expressed in HEK293T cells measured after 2 hrs by TR-FRET assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4836914 | B | Disruption of MKK3/MYC protein-protein interaction in human HCT-116 cells assessed as decrease in MYC level at 0.5 to 10 uM measured by western blot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4836915 | B | Disruption of MKK3/MYC protein-protein interaction in human HCT-116 cells assessed as decrease in CDK4 level at 0.5 to 10 uM measured by western blot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4836916 | B | Disruption of MKK3/MYC protein-protein interaction in human HCT-116 cells assessed as decrease in PDL1 level at 0.5 to 10 uM measured by western blot assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4836917 | B | Disruption of MKK3/MYC protein-protein interaction in human MDA-MB-468 cells assessed as decrease in MYC level at 1 to 20 uM measured by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4836918 | B | Disruption of MKK3/MYC protein-protein interaction in human HCT-116 cells transfected with VF-tagged MKK3 assessed as inhibition of MYC transcriptional activity at 0.5 to 2 uM measured after 12 hrs by Renilla luciferase based reporter assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4836919 | B | Disruption of MKK3/MYC protein-protein interaction in human MDA-MB-468 cells transfected with VF-tagged MKK3 assessed as inhibition of MYC transcriptional activity measured after 12 hrs by Renilla luciferase based reporter assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4836923 | B | Disruption of interaction between human recombinant GST-tagged MKK3/VF-tagged MYC expressed in HEK293T cells at 20 uM measured after 2 hrs by TR-FRET assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA4836924 | B | Disruption of interaction between human recombinant GST-tagged MKK3/VF-tagged MYC expressed in HEK293T cells up to 100 uM measured after 2 hrs by TR-FRET assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4836925 | B | Disruption of interaction between human recombinant GST-tagged MKK3/VF-tagged MYC expressed in HEK293T cells at 50 uM incubated for 30 mins by GST pull-down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4836927 | B | Disruption of interaction between human recombinant GST-tagged MKK3 expressed in HEK293T cells/MYC in human HCT116 cells incubated for 30 mins by GST pull-down assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4836928 | B | Disruption of interaction between human recombinant GST-tagged MKK3/His-tagged MYC HLH LZ domain measured after 2 hrs by TR-FRET assay | Homo sapiens | 1 | protein format | Scientific Literature | ||
| 14. | ALA4836930 | B | Disruption of MKK3/MYC protein-protein interaction in human MDA-MB-468 cells assessed as decrease in CDK4 level at 1 to 20 uM measured by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4836931 | B | Disruption of MKK3/MYC protein-protein interaction in human MDA-MB-468 cells assessed as decrease in PDL1 level at 1 to 20 uM measured by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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