# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4835871 | F | Antiviral activity against HDV infected in human HepG2-NTCP cells assessed as reduction in intranuclear accumulation of HDV delta antigen at 5 uM incubated for 24 hrs followed by replacement with fresh medium and measured at day 5 post infection by DAPI staining based confocal microscopic analysis (Rvb = 12.1 %) | Hepatitis delta virus | 6 | organism-based format | Scientific Literature | ||
2. | ALA4835872 | F | Antiviral activity against HDV infected in human HepG2-NTCP cells assessed as reduction in intranuclear accumulation of HDV delta antigen at 10 uM incubated for 24 hrs followed by replacement with fresh medium and measured at day 5 post infection by DAPI staining based confocal microscopic analysis (Rvb = 12.1 %) | Hepatitis delta virus | 1 | organism-based format | Scientific Literature | ||
3. | ALA5152409 | F | Antiviral activity against hepatitis D virus infected in human Huh-7 cells overexpressing NTCP assessed as reduction in intracellular HDV RNA for 20 hrs followed by viral infection further compound washout and measured after 6 days post infection by RT-qPCR analysis | Hepatitis delta virus | 3 | organism-based format | Scientific Literature | ||
4. | ALA5152414 | F | Antiviral activity against hepatitis D virus infected in human HepG2-hNTCP cells assessed as reduction in viral replication preincubated for 5 mins followed by viral infection measured after 6 hrs post infection by RT-qPCR analysis | Hepatitis delta virus | 3 | organism-based format | Scientific Literature |