# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5043813 | T | Cytotoxicity against Sprague-Dawley rat cardiac fibroblast incubated for 24 hrs by MTT assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
2. | ALA5043826 | T | Cytotoxicity against Sprague-Dawley rat cardiac fibroblast by MTT assay | Rattus norvegicus | 9 | cell-based format | Scientific Literature | ||
3. | ALA5043846 | F | Antifibrotic effect in SD rat cardiac fibroblast assessed as reduction in Ang II-induced collagen I upregulation preincubated for 2 hrs followed by Ang II-stimulation and further incubated for 24 hrs by western blot analysis (Rvb = 71 %) | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
4. | ALA5043847 | F | Antifibrotic effect in SD rat cardiac fibroblast assessed as reduction in Ang II-induced activation of Nrf2 signaling pathway preincubated for 2 hrs followed by Ang II-stimulation and further incubated for 24 hrs by western blot analysis (Rvb = 43 %) | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
5. | ALA5043848 | F | Antifibrotic effect in SD rat cardiac fibroblast transfected with DCN1 siRNA assessed as effect on collagen I expression at 1 uM preincubated for 2 hrs followed by Ang II-stimulation and further incubated for 24 hrs by western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
6. | ALA5043849 | F | Antifibrotic effect in SD rat cardiac fibroblast transfected with DCN1 siRNA assessed as effect on collagen III expression at 1 uM preincubated for 2 hrs followed by Ang II-stimulation and further incubated for 24 hrs by western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
7. | ALA5111482 | T | Cytotoxicity against neonatal rat cardiac fibroblast assessed as cell survival rate at 10 uM measured after 48 hrs by MTT assay relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
8. | ALA5111490 | F | Antimigratory activity in neonatal rat cardiac fibroblasts assessed as fold decrease in Ang II-induced migration measured after 48 hrs by scratch test | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
9. | ALA5111491 | F | Antimigratory activity in neonatal rat cardiac fibroblasts assessed as fold decrease in Ang II-induced migration measured after 48 hrs by transwell test (Rvb = 1.8 fold) | Rattus norvegicus | 1 | cell-based format | Scientific Literature |