# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5141689 | Binding | Protac activity at VHL E3 ligase/GSPT1 in HEK293FT cells assessed as induction of NSD2 degradation at 0.1 to 10 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5137075 | cell-based format | Scientific Literature | |
2. | ALA5152835 | Binding | PROTAC activity at VHL/GSPT1 in human HL-60 cells assessed as effect on GSPT1 protein level at 20 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 3 | ALA5150032 | cell-based format | Scientific Literature | |
3. | ALA5152836 | Binding | PROTAC activity at VHL/GSPT1 in human K562 cells assessed as effect on GSPT1 protein level at 20 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 3 | ALA5150032 | cell-based format | Scientific Literature | |
4. | ALA5152837 | Binding | PROTAC activity at VHL/GSPT1 in human A498 cells assessed as effect on GSPT1 protein level at 20 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 3 | ALA5150032 | cell-based format | Scientific Literature |