| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5151322 | B | PROTAC activity at VHL/HiBit-tagged WDR5 in human MV4-11 cells assessed as induction of WDR5 degradation incubated for 6 to 24 hrs by HiBiT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 2. | ALA5151323 | B | PROTAC activity at VHL/HiBit-tagged WDR5 in human MV4-11 cells assessed as maximum degradation of WDR5 incubated for 6 to 24 hrs by HiBiT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 3. | ALA5151324 | B | PROTAC activity at VHL/HiBit-tagged WDR5 in human MV4-11 cells assessed as maximum degradation of WDR5 incubated for 6 to 24 hrs by HiBiT assay relative to control | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 4. | ALA5151325 | B | PROTAC activity at VHL/HiBit-tagged WDR5 in human MV4-11 cells assessed as induction of WDR5 degradation incubated for 24 hrs by immunoblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA5151326 | B | PROTAC activity at VHL/WDR5 in human MV4-11 cells assessed as induction of WDR5 degradation incubated for 72 hrs by immunoblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA5151327 | B | PROTAC activity at VHL/WDR5 in human MV4-11 cells assessed as reduction in protein stability at 1 uM incubated upto 12 hrs in presence of cycloheximide by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5151328 | B | PROTAC activity at VHL/WDR5 in human MV4-11 cells assessed as reduction in protein stability at 3 uM incubated upto 12 hrs in presence of cycloheximide by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5151329 | B | PROTAC activity at VHL/WDR5 in human MV4-11 cells assessed as decrease in mRNA level at 1 uM incubated for 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5151330 | B | PROTAC activity at VHL/WDR5 in human MV4-11 cells assessed as decrease in mRNA level at 3 uM incubated for 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5151331 | B | PROTAC activity at VHL/WDR5 in human MV4-11 cells assessed as induction of WDR5 degradation at 1 uM incubated for 6 hrs in presence of Tert-Butyl 3'-(6-Hydroxy-4-(trifluoromethyl)-nicotinamido)-4'-(4-methylpiperazin-1-yl)-[1,1'-biphenyl]-4-carboxylate by qRT-PCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5151332 | B | PROTAC activity at VHL/WDR5 in human MV4-11 cells assessed as induction of WDR5 degradation at 3 uM incubated for 6 hrs in presence of MG132 by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5151333 | B | PROTAC activity at VHL/WDR5 in human MV4-11 cells assessed as induction of WDR5 degradation at 3 uM incubated for 6 hrs in presence of MLN4924 by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5151334 | B | PROTAC activity at VHL/WDR5 in human HL-60 cells assessed as induction of WDR5 degradation upto 10 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5151335 | B | PROTAC activity at VHL/WDR5 in human MV4-11 cells assessed as induction of WDR5 degradation at 1 uM incubated for 9 hrs by mass spectrometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA5151336 | B | PROTAC activity at VHL/WDR5 in human MV4-11 cells assessed as induction of WDR5 degradation at 5 uM incubated for 9 hrs by mass spectrometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA5151342 | B | PROTAC activity at VHL/HiBit-tagged WDR5 in human MV4-11 cells assessed as induction of WDR5 degradation incubated for 24 hrs by HiBiT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA5151343 | B | PROTAC activity at VHL/HiBit-tagged WDR5 in human MV4-11 cells assessed as maximum degradation upto 10 uM incubated for 24 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5151344 | B | PROTAC activity at VHL/HiBit-tagged WDR5 in human MV4-11 cells assessed as maximum degradation upto 10 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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