# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5160158 | B | Protac activity at VHL/SOS2 in human NCI-H358 cells assessed as SOS2 protein degradation at 9.8 to 2500 nM incubated for 24 hr by Western blot analysis | Homo sapiens | 1 | ALA5154769 | cell-based format | Scientific Literature | |
2. | ALA5160174 | B | Protac activity at VHL/SOS2 in human NCI-H358 cells assessed as SOS2 mRNA level at 1 uM incubated for 24 to 72 hr by qRT PCR analysis | Homo sapiens | 1 | ALA5154769 | cell-based format | Scientific Literature | |
3. | ALA5160208 | B | Protac activity at VHL/SOS2 in human NCI-H358 cells assessed as SOS2 protein degradation at 2.5 uM incubated for 24 hr by Western blot analysis | Homo sapiens | 1 | ALA5154769 | cell-based format | Scientific Literature | |
4. | ALA5160209 | B | Protac activity at VHL/SOS2 in human ASPC1 cells assessed as SOS2 mRNA level at 1 uM incubated for 24 to 72 hr by qRT PCR analysis | Homo sapiens | 1 | ALA5154769 | cell-based format | Scientific Literature |