# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5126117 | Binding | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as induction of CDK13 degradation at 1 uM incubated for 15 hrs by immunoblotting analysis relative to control | Homo sapiens | 27 | ALA5120962 | cell-based format | Scientific Literature | |
2. | ALA5126118 | Binding | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as induction of CDK13 degradation incubated for 15 hrs by immunoblotting analysis | Homo sapiens | 8 | ALA5120962 | cell-based format | Scientific Literature | |
3. | ALA5126120 | Binding | Protac activity at CRBN/CDK13 in human MFM-223 cells assessed as induction of degradation by Western blotting analysis | Homo sapiens | 1 | ALA5120962 | cell-based format | Scientific Literature | |
4. | ALA5126122 | Binding | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as induction of degradation by Western blotting analysis | Homo sapiens | 1 | ALA5120962 | cell-based format | Scientific Literature | |
5. | ALA5126125 | Binding | Protac activity at CRBN/CDK13 in human MFM-223 cells assessed as induction of degradation at 500 nM measured after 4 hrs by Western blotting analysis | Homo sapiens | 1 | ALA5120962 | cell-based format | Scientific Literature | |
6. | ALA5126126 | Binding | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as induction of degradation at 500 nM measured after 4 hrs by Western blotting analysis | Homo sapiens | 1 | ALA5120962 | cell-based format | Scientific Literature | |
7. | ALA5126128 | Binding | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as degradation of CDK13 at 500 nM measured after 6 hrs in presence of carfilzomib by Western blot analysis | Homo sapiens | 1 | ALA5120962 | cell-based format | Scientific Literature | |
8. | ALA5126130 | Binding | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as degradation of CDK13 at 500 nM measured after 6 hrs in presence of bafilomycin by Western blot analysis | Homo sapiens | 1 | ALA5120962 | cell-based format | Scientific Literature | |
9. | ALA5126132 | Binding | Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as inhibition of degradation of CDK13 at 500 nM measured after 6 hrs presence of thalidomide | Homo sapiens | 1 | ALA5120962 | cell-based format | Scientific Literature |