# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5130723 | Binding | Protac activity at VHL/HDAC4 in mouse Neuro2a cells assessed as induction of HDAC4 degradation incubated for 24 hrs in absence of elacridar by Western blot analysis | Mus musculus | 1 | ALA5126633 | cell-based format | Scientific Literature | |
2. | ALA5130724 | Binding | Protac activity at VHL/HDAC4 in mouse Neuro2a cells assessed as induction of HDAC4 degradation preincubated with elacridar for 1 hr followed by compound addition and measured after 24 hrs by Western blot analysis | Mus musculus | 1 | ALA5126633 | cell-based format | Scientific Literature | |
3. | ALA5130725 | Binding | Protac activity at VHL/HDAC4 in Q175 KI mouse cortical neuron assessed as induction of HDAC4 degradation incubated for 4 to 72 hrs in absence of elacridar by MSD assay | Mus musculus | 1 | ALA5126633 | cell-based format | Scientific Literature | |
4. | ALA5130726 | Binding | Protac activity at VHL/HDAC4 in Q175 KI mouse cortical neuron assessed as induction of HDAC4 degradation preincubated with elacridar for 1 hr followed by compound addition and measured after 4 to 72 hrs by MSD assay | Mus musculus | 1 | ALA5126633 | cell-based format | Scientific Literature |