# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5119591 | B | Inhibition of CDK8 in mouse BMDC cells assessed as reduction in IFNgamma-induced STAT1 phosphorylation at S727 residue pretreated with IFNgamma for 2 hrs followed by compound treatment for 24 hrs by Western blot assay | Mus musculus | 1 | ALA5113525 | cell-based format | Scientific Literature | |
2. | ALA5166991 | B | Inhibition of CDK8 in IFN-gamma-stimulated mouse BMDC cells assessed as STAT-1 phosphorylation at Ser727 at 1 to 4 uM treated for 2 hrs followed by IFN-gamma stimulation for 12 hrs by western blot analysis | Mus musculus | 1 | ALA5154907 | cell-based format | Scientific Literature | |
3. | ALA5166995 | B | Inhibition of CDK8 in R848-stimulated mouse BMDC cells assessed as downregulation of c-Jun phosphorylation at Ser243 at 1 to 4 uM treated for 2 hrs followed by R848 stimulation for 12 hrs by western blot analysis | Mus musculus | 1 | ALA5154907 | cell-based format | Scientific Literature | |
4. | ALA5166996 | B | Inhibition of CDK8 in R848-stimulated mouse BMDC cells assessed as effect on CRTC3 phosphorylation at Ser370 at 1 to 4 uM treated for 2 hrs followed by R848 stimulation for 12 hrs by western blot analysis | Mus musculus | 1 | ALA5154907 | cell-based format | Scientific Literature |