| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5105491 | B | Thermal stabilization of quadruplex DNA (unknown origin) | Not specified | 1 | ALA5104123 | nucleic acid format | Scientific Literature | |
| 2. | ALA5110054 | B | Binding affinity to Trypanosoma brucei G-quadruplex telomeric DNA FEBR1T (5'-duplex GGG TTAGGG TTAGGG TTAGGG-3') assessed as stabilization by measuring change in melting temperature at 10 uM in potassium buffer by FRET melting assay | Trypanosoma brucei | 19 | ALA5108010 | nucleic acid format | Scientific Literature | |
| 3. | ALA5110075 | B | Binding affinity to Trypanosoma brucei G-quadruplex telomeric DNA FEBR1T (5'-duplex GGG TTAGGG TTAGGG TTAGGG-3') assessed as stabilization by measuring change in melting temperature at 1 uM in potassium buffer by FRET melting assay | Trypanosoma brucei | 1 | ALA5108010 | nucleic acid format | Scientific Literature | |
| 4. | ALA5224614 | B | Binding affinity to c-KIT1 G4 quadruplex DNA (unknown origin) assessed as change in melting temperature at 1:2 G4:ligand ratio by UV analysis (Rvb = 66.5 degreeC) | Not specified | 1 | ALA5223108 | nucleic acid format | Scientific Literature | |
| 5. | ALA5224615 | B | Binding affinity to c-KIT2 G4 quadruplex DNA (unknown origin) assessed as change in melting temperature at 1:2 G4:ligand ratio by UV analysis (Rvb = 59.1 degreeC) | Not specified | 1 | ALA5223108 | nucleic acid format | Scientific Literature | |
| 6. | ALA5224616 | B | Binding affinity to 22AG_K G4 quadruplex DNA (unknown origin) assessed as change in melting temperature at 1:2 G4:ligand ratio by UV analysis (Rvb = 60.1 degreeC) | Not specified | 1 | ALA5223108 | nucleic acid format | Scientific Literature | |
| 7. | ALA5224617 | B | Binding affinity to KRAS G4 quadruplex DNA (unknown origin) assessed as change in melting temperature at 1:2 G4:ligand ratio by UV analysis (Rvb = 48.7 degreeC) | Not specified | 1 | ALA5223108 | nucleic acid format | Scientific Literature | |
| 8. | ALA5224618 | B | Binding affinity to 22AG_Na G4 quadruplex DNA (unknown origin) assessed as change in melting temperature at 1:2 G4:ligand ratio by UV analysis (Rvb = 55.9 degreeC) | Not specified | 1 | ALA5223108 | nucleic acid format | Scientific Literature | |
| 9. | ALA5224619 | B | Binding affinity to 23TA G4 quadruplex DNA (unknown origin) assessed as change in melting temperature at 1:2 G4:ligand ratio by UV analysis (Rvb = 59.5 degreeC) | Not specified | 1 | ALA5223108 | nucleic acid format | Scientific Literature | |
| 10. | ALA5224624 | B | Binding affinity to c-KIT1 G4 quadruplex DNA (unknown origin) by CD spectroscopy analysis | Not specified | 1 | ALA5223108 | nucleic acid format | Scientific Literature | |
| 11. | ALA5224625 | B | Binding affinity to 22AG_Na G4 quadruplex DNA (unknown origin) by CD spectroscopy analysis | Not specified | 1 | ALA5223108 | nucleic acid format | Scientific Literature | |
| 12. | ALA5225123 | B | Binding affinity to G4-quadruplex DNA (unknown origin) assessed as inhibition of Taq polymerase at G4 site on DNA template at 0.01 to 10 uM by autoradiogram | Not specified | 1 | ALA5223131 | nucleic acid format | Scientific Literature | |
| 13. | ALA5225124 | B | Binding affinity to G4-quadruplex DNA (unknown origin) assessed as inhibition of Taq polymerase at G4 site on DNA template by measuring fold increase intensity of band at G4 pause site at 0.01 to 10 uM by autoradiogram | Not specified | 1 | ALA5223131 | nucleic acid format | Scientific Literature | |
| 14. | ALA5235455 | B | Binding affinity to MYC G4-quadruplex DNA (unknown origin) assessed as dissociation constant | Not specified | 3 | ALA5233264 | nucleic acid format | Scientific Literature | |
| 15. | ALA5243799 | B | Stabilization and preservation of G-quadruplex homo-purine guanine-rich GA1 (GAGGGAGGGAGGGAAAAGGGGA) DNA (unknown origin) parallel structure conformation at 2 equivalents in 100K buffer by circular dichroism scan analysis | Not specified | 1 | ALA5241123 | nucleic acid format | Scientific Literature | |
| 16. | ALA5243800 | B | Stabilization and preservation of G-quadruplex homo-purine guanine-rich GA2 (GAGGGAGGGAAAAGGGGAGGGA) DNA (unknown origin) parallel structure conformation at 2 equivalents in 100K buffer by circular dichroism scan analysis | Not specified | 1 | ALA5241123 | nucleic acid format | Scientific Literature | |
| 17. | ALA5243801 | B | Stabilization and preservation of G-quadruplex homo-purine guanine-rich GA3 (AGGGAAAAGGGGAGGGAAAAGGGGA) DNA (unknown origin) parallel structure conformation at 2 equivalents in 100K buffer by circular dichroism scan analysis | Not specified | 1 | ALA5241123 | nucleic acid format | Scientific Literature | |
| 18. | ALA5243802 | B | Stabilization and preservation of G-quadruplex homo-purine guanine-rich GA1 (GAGGGAGGGAGGGAAAAGGGGA) DNA (unknown origin) parallel structure conformation assessed as increased homogeneity at 2 equivalents in 100K buffer by native PAGE analysis | Not specified | 1 | ALA5241123 | nucleic acid format | Scientific Literature | |
| 19. | ALA5243803 | B | Stabilization and preservation of G-quadruplex homo-purine guanine-rich GA2 (GAGGGAGGGAAAAGGGGAGGGA) DNA (unknown origin) parallel structure conformation assessed as elimination of higher order species at 2 equivalents in 100K buffer by native PAGE analysis | Not specified | 1 | ALA5241123 | nucleic acid format | Scientific Literature | |
| 20. | ALA5243804 | B | Stabilization and preservation of G-quadruplex homo-purine guanine-rich GA3 (AGGGAAAAGGGGAGGGAAAAGGGGA) DNA (unknown origin) parallel structure conformation at 2 equivalents in 100K buffer by native PAGE analysis | Not specified | 1 | ALA5241123 | nucleic acid format | Scientific Literature |
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