# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5254602 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced IkappaBalpha phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
2. | ALA5254603 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced ERK phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
3. | ALA5254604 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced p-38 phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
4. | ALA5254605 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced JNK phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
5. | ALA5254606 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced IkappaBalpha protein expression level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
6. | ALA5254607 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced IkappaBalpha phosphorylation level at 10 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
7. | ALA5254608 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced ERK phosphorylation level at 10 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
8. | ALA5254609 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced p-38 phosphorylation level at 10 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
9. | ALA5254610 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced JNK phosphorylation level at 10 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
10. | ALA5254611 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced IkappaBalpha protein expression level at 10 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
11. | ALA5254612 | B | Antagonist activity at NOD1 in LPS induced mouse peritoneal macrophage assessed as decrease in C12-iE-DAP/LPS-induced IL-6 expression level at 5 to 20 uM preincubated for 3 hr followed by C12-iE-DAP addition and measured after 24 hr by ELISA | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
12. | ALA5254613 | B | Antagonist activity at NOD1 in LPS induced mouse peritoneal macrophage assessed as decrease in C12-iE-DAP/LPS-induced TNF-alpha expression level at 5 to 20 uM preincubated for 3 hr followed by C12-iE-DAP addition and measured after 24 hr by ELISA | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature |