# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA691888 | F | Inhibition HCV RNA replication | Hepacivirus hominis | 21 | ALA1149159 | assay format | Scientific Literature | |
2. | ALA691889 | F | Inhibition HCV NS5B-mediated RNA synthesis | Hepacivirus hominis | 19 | ALA1149159 | assay format | Scientific Literature | |
3. | ALA750248 | B | Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity. | Hepacivirus hominis | 32 | ALA1149207 | single protein format | Scientific Literature | |
4. | ALA750249 | B | Inhibitory activity against NS5B polymerase of hepatitis C virus | Hepacivirus hominis | 1 | ALA1149223 | single protein format | Scientific Literature | |
5. | ALA750250 | B | Inhibitory activity against NS5B polymerase of hepatitis C virus | Hepacivirus hominis | 47 | ALA1149223 | single protein format | Scientific Literature | |
6. | ALA750251 | B | Inhibitory activity against NS5B polymerase of hepatitis C virus at 7 uM concentration; (Range = 13-30) | Hepacivirus hominis | 1 | ALA1149223 | single protein format | Scientific Literature | |
7. | ALA750252 | B | Ability of compound to displace [3H]-DKA from NS5B HCV polymerase by 50% | Hepacivirus hominis | 2 | ALA1146656 | single protein format | Scientific Literature | |
8. | ALA750253 | B | Inhibitory potency against NS5B HCV polymerase | Hepacivirus hominis | 11 | ALA1146656 | single protein format | Scientific Literature | |
9. | ALA750254 | B | Inhibitory potency of compound in presence of Mg2+ ion against NS5B HCV polymerase | Hepacivirus hominis | 5 | ALA1146656 | single protein format | Scientific Literature | |
10. | ALA750255 | B | Inhibitory potency of compound in presence of Mn2+ ion against NS5B HCV polymerase | Hepacivirus hominis | 5 | ALA1146656 | single protein format | Scientific Literature | |
11. | ALA768322 | B | Inhibitory activity against Hepatitis C virus RNA dependent RNA polymerase nonstructural protein 5B | Hepacivirus hominis | 31 | ALA1139456 | single protein format | Scientific Literature | |
12. | ALA766521 | B | Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected Sf9 insect cells | Hepacivirus hominis | 22 | ALA1144916 | cell-based format | Scientific Literature | |
13. | ALA828787 | F | Inhibition constant against ATP binding towards Hepatitis C Virus NS5BRdRp | Hepacivirus hominis | 3 | ALA1143599 | assay format | Scientific Literature | |
14. | ALA826387 | F | Steady-state kinetic constant for Hepatitis C Virus NS5BRdRp | Hepacivirus hominis | 3 | ALA1143599 | assay format | Scientific Literature | |
15. | ALA839075 | B | Cytotoxic concentration against RNA dependent RNA polymerase Nonstructural protein 5B (HCV NS5B polymerase) in Hepatitis C virus | Hepacivirus hominis | 48 | ALA1145278 | single protein format | Scientific Literature | |
16. | ALA829179 | B | Effective concentration for inhibitory activity against NS5B polymerase of Hepatitis C virus; n=1 | Hepacivirus hominis | 1 | ALA1142688 | single protein format | Scientific Literature | |
17. | ALA839761 | B | Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1 | Hepacivirus hominis | 12 | ALA1142688 | single protein format | Scientific Literature | |
18. | ALA877122 | B | Effective concentration for inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virus; n=1 | Hepacivirus hominis | 1 | ALA1142688 | single protein format | Scientific Literature | |
19. | ALA839779 | B | Effective concentration against RNA dependent RNA polymerase Nonstructural protein 5B of genotype 1b Hepatitis C virus | Hepacivirus hominis | 6 | ALA1142034 | single protein format | Scientific Literature | |
20. | ALA830043 | B | Effective concentration against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virus; n=1, nd= not determined | Hepacivirus hominis | 1 | ALA1142688 | single protein format | Scientific Literature |