# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5225895 | F | Antiproliferative activity against human 5-8F cells assessed as cell viability at 80 uM incubated for 72 hrs by CCK-8 assay | Homo sapiens | 14 | ALA5223175 | cell-based format | Scientific Literature | |
2. | ALA5225898 | F | Antiproliferative activity against human 5-8F cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay | Homo sapiens | 2 | ALA5223175 | cell-based format | Scientific Literature | |
3. | ALA5225902 | F | Antiproliferative activity against human 5-8F cells assessed as reduction in cell viability at 5 to 40 uM incubated for 48 hrs by CCK-8 assay | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
4. | ALA5225904 | F | Inhibition of colony formation in human 5-8F cells at 10 to 30 uM replaced with fresh medium for every 3 days and measured for 10 to 15 days by Giemsa staining based assay | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
5. | ALA5225905 | F | Antiproliferative activity against human 5-8F cells assessed as reduction in Ki67 expression at 10 to 30 uM by Western blotting analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
6. | ALA5225907 | F | Induction of apoptosis in human 5-8F cells assessed as appearance of rounded cells incubated for 48 hrs by microscopic analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
7. | ALA5225908 | F | Induction of apoptosis in human 5-8F cells assessed as appearance of floating cells incubated for 48 hrs by microscopic analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
8. | ALA5225909 | F | Induction of apoptosis in human 5-8F cells assessed as increase in dead cells incubated for 48 hrs by microscopic analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
9. | ALA5225910 | F | Induction of apoptosis in human 5-8F cells at 30 uM incubated for 48 hrs by Annexin V-FITC and PI staining based flow cytometry analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
10. | ALA5225911 | F | Induction of apoptosis in human 5-8F cells assessed as downregulation of procaspase-3 expression at 10 to 30 uM incubated for 48 hrs by Western blotting analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
11. | ALA5225912 | F | Induction of apoptosis in human 5-8F cells assessed as downregulation of Bcl-2 expression at 10 to 30 uM incubated for 48 hrs by Western blotting analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
12. | ALA5225913 | F | Induction of apoptosis in human 5-8F cells assessed as upregulation of p53 expression at 10 to 30 uM incubated for 48 hrs by Western blotting analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
13. | ALA5225914 | F | Induction of apoptosis in human 5-8F cells assessed as upregulation of Bax expression at 10 to 30 uM incubated for 48 hrs by Western blotting analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
14. | ALA5225915 | F | Induction of apoptosis in human 5-8F cells assessed as upregulation of cleaved PARP expression at 10 to 30 uM incubated for 48 hrs by Western blotting analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
15. | ALA5225916 | F | Induction of autophagy in human 5-8F cells assessed as increase in LC3 puncta accumulation at 30 uM incubated for 48 hrs by confocal microscopy analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
16. | ALA5225917 | F | Induction of autophagy in human 5-8F cells assessed as appearance of autophagic vacuoles at 30 uM incubated for 48 hrs by TEM analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
17. | ALA5225918 | F | Induction of autophagy in human 5-8F cells assessed as increase in LC3I to LC3II conversion at 10 to 30 uM by Western blotting analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
18. | ALA5225919 | F | Induction of autophagy in human 5-8F cells assessed as increase in Beclin-1 expression at 10 to 30 uM by Western blotting analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
19. | ALA5225920 | F | Induction of autophagy in human 5-8F cells assessed as decrease in p62 expression at 10 to 30 uM by Western blotting analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature | |
20. | ALA5225921 | F | Induction of ferroptosis in human 5-8F cells assessed as change in mitochondrial morphology at 30 uM incubated for 48 hrs by TEM analysis | Homo sapiens | 1 | ALA5223175 | cell-based format | Scientific Literature |