| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5238740 | B | PROTAC activity at PAK1/CRBN in human MCF7 cells assessed as PAK1 degradation measured after 24 hrs by immunoblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA5238741 | B | PROTAC activity at PAK1/CRBN in human OVACR-3 cells assessed as PAK1 degradation measured after 24 hrs by immunoblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA5238744 | B | PROTAC activity at PAK1/CRBN in human MCF7 cells assessed as PAK1 degradation measured at 10 nM by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5238745 | B | PROTAC activity at PAK1/CRBN in human MCF7 cells assessed as PAK1 degradation in presence of bortezomib measured after 24 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5238746 | B | PROTAC activity at PAK1/CRBN in human OVACR-3 cells assessed as PAK1 degradation in presence of bortezomib measured after 24 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5238750 | B | PROTAC activity at PAK1/CRBN in HEK293 cells transfected with Nluc-tagged PAK1 assessed as PAK1 degradation by measuring luciferase activity at 10 nM by Nano-Glo live cell assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5238751 | B | PROTAC activity at PAK1/CRBN in human MCF7 cells assessed as MEK phosphorylation at S298 at 10 nM measured after 24 hrs by immunoblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA5238752 | B | PROTAC activity at PAK1/CRBN in human MCF7 cells assessed as ERK phosphorylation at Thr202/Tyr204 at 10 nM measured after 24 hrs by immunoblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA5238753 | B | PROTAC activity at PAK1/CRBN in human OVACR3 cells assessed as MEK phosphorylation at S298 at 10 nM measured after 24 hrs by immunoblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA5238754 | B | PROTAC activity at PAK1/CRBN in human OVACR3 cells assessed as ERK phosphorylation at Thr202/Tyr204 at 10 nM measured after 24 hrs by immunoblot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |
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