| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA749388 | B | Compound was evaluated for its blocking effect against N-methyl-D-aspartate glutamate receptor 2B | xenopus oocytes | 1 | ALA1131319 | single protein format | Scientific Literature | |
| 2. | ALA749676 | B | Ability to displace of racemic 13 % of [3H]CP-101606 binding to N-methyl-D-aspartate glutamate receptor 2B in rat forebrain membranes. | 1 | ALA1131319 | cell membrane format | Scientific Literature | ||
| 3. | ALA749822 | B | Ability to displace of racemic [3H]CP-101606 binding to N-methyl-D-aspartate glutamate receptor 2B in rat forebrain membranes; Not tested | 5 | ALA1131319 | cell membrane format | Scientific Literature | ||
| 4. | ALA749823 | B | Inhibitory activity against N-methyl-D-aspartate glutamate receptor 2B in rat | 2 | ALA1136222 | assay format | Scientific Literature | ||
| 5. | ALA752255 | B | Evaluated for in vitro inhibition of recombinant rat NR1C/2B receptor expressed in xenopus oocytes | 1 | ALA1133913 | cell-based format | Scientific Literature | ||
| 6. | ALA747851 | B | The compound was evaluated in vitro for its inhibition against xenopus oocytes expressing recombinant rat NR1C/2B receptor; ND means Not determined | 1 | ALA1133913 | cell-based format | Scientific Literature | ||
| 7. | ALA909221 | B | Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membrane | Rattus norvegicus | 18 | ALA1148684 | cell membrane format | Scientific Literature | |
| 8. | ALA907918 | B | Receptor occupancy ex vivo by displacement of [3H](E)-N1-(2-methoxybenzyl)-cinnamamidine binding from NR2B in rat brain at 10 uM | Rattus norvegicus | 1 | ALA1141373 | tissue-based format | Scientific Literature | |
| 9. | ALA914283 | F | Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium concentration | Rattus norvegicus | 57 | ALA1142862 | cell-based format | Scientific Literature | |
| 10. | ALA914284 | B | Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrain | Rattus norvegicus | 57 | ALA1142862 | assay format | Scientific Literature | |
| 11. | ALA899623 | B | Displacement of [3H]CP-101606 from NR2B in rat forebrain P2 membrane | Rattus norvegicus | 22 | ALA1137458 | cell membrane format | Scientific Literature | |
| 12. | ALA940926 | B | Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membrane | Rattus norvegicus | 19 | ALA1139807 | cell membrane format | Scientific Literature | |
| 13. | ALA940934 | B | Displacement of [3H]racemic CP-101606 from rat NR2B receptor in P2 membrane | Rattus norvegicus | 23 | ALA1139808 | cell membrane format | Scientific Literature | |
| 14. | ALA933576 | B | Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor | Rattus norvegicus | 12 | ALA1145640 | assay format | Scientific Literature | |
| 15. | ALA933577 | B | Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor relative to ifenprodil | Rattus norvegicus | 12 | ALA1145640 | assay format | Scientific Literature | |
| 16. | ALA974282 | B | Inhibition of rat NMDA NR2B receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at 1 uM at -70 mV by voltage clamp method | Rattus norvegicus | 2 | ALA1156530 | cell-based format | Scientific Literature | |
| 17. | ALA974284 | B | Inhibition of rat NMDA NR2B receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -70 mV by voltage clamp method | Rattus norvegicus | 5 | ALA1156530 | cell-based format | Scientific Literature | |
| 18. | ALA1036615 | B | Inhibition of rat NR1/NR2B(E201R) mutant receptor expressed in Xenopus oocytes at 100 nM by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA1140127 | cell-based format | Scientific Literature | |
| 19. | ALA1034045 | F | Antagonist activity at NMDA NR2B receptor in Wistar rat CA1 pyramidal neurons assessed as reduction of NMDA-induced inward currents at 100 uM at holding potential of -60 mV by patch-clamp technique | Rattus norvegicus | 1 | ALA1152695 | cell-based format | Scientific Literature | |
| 20. | ALA1034046 | F | Antagonist activity at NMDA NR2B receptor in Wistar rat CA1 pyramidal neurons assessed as reduction of NMDA-induced inward currents at 10 uM at holding potential of -60 mV by patch-clamp technique | Rattus norvegicus | 1 | ALA1152695 | cell-based format | Scientific Literature |
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