# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3607229 | Binding | Antagonist activity against glucocorticoid receptor in rat H4-IIE cells assessed as inhibition of dexamethasone-induced receptor transactivation pre-incubated for 1 hr before dexamethasone addition and measured 24 hrs post dexamethasone stimulation by tyrosine aminotransferase enzyme assay | Rattus norvegicus | 8 | ALA3603837 | cell-based format | Scientific Literature | |
2. | ALA3607231 | Binding | Agonist activity at glucocorticoid receptor in rat H4-IIE cells assessed as receptor transactivation incubated for 24 hrs by tyrosine aminotransferase enzyme assay | Rattus norvegicus | 5 | ALA3603837 | cell-based format | Scientific Literature | |
3. | ALA3624119 | Binding | Inhibition of rat glucocorticoid receptor at 10 uM relative to control | Rattus norvegicus | 2 | ALA3621160 | single protein format | Scientific Literature | |
4. | ALA3737649 | Binding | Antagonist activity at glucocorticoid receptor in rat H4IIEC3 cells assessed as glucocorticoid-induced TAT activity | Rattus norvegicus | 1 | ALA3734698 | cell-based format | Scientific Literature | |
5. | ALA3737655 | Binding | Antagonist activity at glucocorticoid receptor in rat primary hepatocytes assessed as inhibition of glucocorticoid-induced TAT activity relative to control | Rattus norvegicus | 1 | ALA3734698 | cell-based format | Scientific Literature | |
6. | ALA3737657 | Binding | Agonist activity at glucocorticoid receptor in rat primary hepatocytes assessed as inhibition of glucocorticoid-induced TAT activity relative to control | Rattus norvegicus | 1 | ALA3734698 | cell-based format | Scientific Literature | |
7. | ALA3736643 | Binding | Antagonist activity at glucocorticoid receptor in rat primary hepatocytes assessed as inhibition of glucocorticoid-induced TAT activity | Rattus norvegicus | 2 | ALA3734698 | cell-based format | Scientific Literature | |
8. | ALA3736645 | Binding | Agonist activity at glucocorticoid receptor in rat primary hepatocytes assessed as inhibition of glucocorticoid-induced TAT activity | Rattus norvegicus | 1 | ALA3734698 | cell-based format | Scientific Literature | |
9. | ALA685135 | Binding | Relative binding affinity for glucocorticoid receptor | Rattus norvegicus | 3 | ALA1122289 | single protein format | Scientific Literature | |
10. | ALA685136 | Binding | Relative binding affinity against glucocorticoid receptor in rat liver cytosol extract | Rattus norvegicus | 7 | ALA1127640 | assay format | Scientific Literature | |
11. | ALA685137 | Binding | Steroid binding against the rat thymus glucocorticoid receptor | 19 | ALA1129589 | single protein format | Scientific Literature | ||
12. | ALA685138 | Binding | Competitive displacement of [3H]dexamethasone from glucocorticoid receptor of rat liver cytosol | Rattus norvegicus | 7 | ALA1125859 | assay format | Scientific Literature | |
13. | ALA685139 | Binding | Competitive displacement of [3H]dexamethasone from glucocorticoid receptor of rat liver cytosol; ND = not determined | Rattus norvegicus | 2 | ALA1125859 | assay format | Scientific Literature | |
14. | ALA679999 | Binding | Dex-NCS incubation on the subsequent inhibition of exchange binding with [3H]dexamethasone measured at pH 7.6 at 1h. | Rattus norvegicus | 1 | ALA1125707 | single protein format | Scientific Literature | |
15. | ALA680000 | Binding | Dex-NCS incubation on the subsequent inhibition of exchange binding with [3H]Dexamethasone measured at pH 7.6 at 20h. | Rattus norvegicus | 1 | ALA1125707 | single protein format | Scientific Literature | |
16. | ALA680001 | Binding | Dex-NCS incubation on the subsequent inhibition of exchange binding with [3H]dexamethasone measured at pH 7.6 at 3h. | Rattus norvegicus | 1 | ALA1125707 | single protein format | Scientific Literature | |
17. | ALA685726 | Binding | Dex-NCS incubation on the subsequent inhibition of exchange binding with [3H]dexamethasone measured at pH 7.6 at 5h. | Rattus norvegicus | 1 | ALA1125707 | single protein format | Scientific Literature | |
18. | ALA685727 | Binding | Dex-NCS incubation on the subsequent inhibition of exchange binding with [3H]dexamethasone measured at pH 8.8 at 1h. | Rattus norvegicus | 1 | ALA1125707 | single protein format | Scientific Literature | |
19. | ALA685728 | Binding | Dex-NCS incubation on the subsequent inhibition of exchange binding with [3H]dexamethasone measured at pH 8.8 at 3h. | Rattus norvegicus | 1 | ALA1125707 | single protein format | Scientific Literature | |
20. | ALA685729 | Binding | Dex-NCS incubation on the subsequent inhibition of exchange binding with [3H]dexamethasone measured at pH 8.8 at 5h. | Rattus norvegicus | 1 | ALA1125707 | single protein format | Scientific Literature |