# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5264424 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as BRD9 protein degradation in the presence of MG132 by Western blot analysis | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
2. | ALA5264432 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as BRD9 protein degradation at 100 nM incubated for 4 hrs by MS proteomics analysis | Homo sapiens | 2 | ALA5260840 | cell-based format | Scientific Literature | |
3. | ALA5264435 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as BRD9 protein degradation at 100 nM incubated for 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
4. | ALA5264437 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as BRD9 protein degradation at 100 nM pre-incubated for 30 mins with VH298 followed by compound addition and measured after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
5. | ALA5264439 | Binding | PROTAC activity at VHL/HiBiT-tagged BRD9 expressed in HEK293 assessed as BRD9 ubiquitination at 1 uM measured upto 60 mins by NanoBRET assay | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
6. | ALA5264441 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as BRD9 protein degradation in the presence of MLN4924 by Western blot analysis | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
7. | ALA5264450 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 100 nM incubated for 48 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
8. | ALA5264451 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 10 nM incubated for 48 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
9. | ALA5264452 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 100 nM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
10. | ALA5264453 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 10 nM incubated for 4 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
11. | ALA5264454 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 10 nM incubated for 1 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
12. | ALA5264455 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 100 nM incubated for 4 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
13. | ALA5264456 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 10 nM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
14. | ALA5264457 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 100 nM incubated for 1 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
15. | ALA5264458 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 100 nM incubated for 30 mins by Western blot analysis relative to control | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
16. | ALA5264459 | Binding | PROTAC activity at VHL/BRD9 in human Ri-1 cells assessed as remaining BRD9 protein level at 10 nM incubated for 30 mins by Western blot analysis relative to control | Homo sapiens | 1 | ALA5260840 | cell-based format | Scientific Literature | |
17. | ALA5264460 | Binding | PROTAC activity at VHL/BRD9 in human HeLa cells assessed as remaining BRD9 protein level at 1 uM incubated for 4 hrs by Western blot analysis relative to control | Homo sapiens | 32 | ALA5260840 | cell-based format | Scientific Literature | |
18. | ALA5264461 | Binding | PROTAC activity at VHL/BRD9 in human HeLa cells assessed as remaining BRD9 protein level at 1 uM incubated for 16 hrs by Western blot analysis relative to control | Homo sapiens | 12 | ALA5260840 | cell-based format | Scientific Literature | |
19. | ALA5264473 | Binding | PROTAC activity at VHL/BRD9 in human HeLa cells assessed as protein degradation at 1 uM incubated for 4 hrs by Western blot analysis relative to control | Homo sapiens | 3 | ALA5260840 | cell-based format | Scientific Literature | |
20. | ALA5264475 | Binding | PROTAC activity at VHL/BRD9 in human HeLa cells assessed as protein degradation at 1 uM incubated for 16 hrs by Western blot analysis relative to control | Homo sapiens | 2 | ALA5260840 | cell-based format | Scientific Literature |