| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5254702 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current amplitude at -80 mV holding potential in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 2. | ALA5254703 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current amplitude at -80 mV holding potential in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 3. | ALA5254708 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced current at -80 mV holding potential at 1 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 4. | ALA5254712 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal current at -80 mV holding potential in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 5. | ALA5254713 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal current at -80 mV holding potential in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 6. | ALA5254726 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current amplitude at -80 mV holding potential under more potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 7. | ALA5254727 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current amplitude at -80 mV holding potential under less potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 8. | ALA5254728 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal current at -80 mV holding potential under more potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay relative to control | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 9. | ALA5254729 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal current at -80 mV holding potential under less potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay relative to control | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 10. | ALA5254738 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current amplitude at -80 mV holding potential under less potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 11. | ALA5254739 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal current at -80 mV holding potential under less potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay relative to control | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 12. | ALA5254767 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 1 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 13. | ALA5254768 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 3 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 14. | ALA5254769 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 10 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 15. | ALA5254770 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 30 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 16. | ALA5254771 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 100 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 17. | ALA5254772 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 300 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 18. | ALA5254773 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 1 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 19. | ALA5254774 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 3 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature | |
| 20. | ALA5254775 | B | Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 10 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | ALA5252552 | cell-based format | Scientific Literature |
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