# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4190832 | A | Cytotoxicity against rat primary cortical astrocytes assessed as reduction in cell viability at 5 to 40 uM after 48 hrs by MTT assay relative to control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
2. | ALA4431911 | F | Neuroprotective activity in Sprague-Dawley rat astrocytes assessed as effect on vimentin positive cell density and morphology at 10 uM by fluorescence microscopic method | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
3. | ALA4431912 | F | Neuroprotective activity in Sprague-Dawley rat astrocytes assessed as effect on vimentin positive cell density and morphology at 50 uM by fluorescence microscopic method | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
4. | ALA4431913 | F | Neuroprotective activity in Sprague-Dawley rat astrocytes assessed as effect on vimentin positive cell density and morphology at 100 uM by fluorescence microscopic method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
5. | ALA4431914 | F | Neuroprotective activity in Sprague-Dawley rat astrocytes assessed as effect on vimentin positive cell density and morphology at 1 mM by fluorescence microscopic method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
6. | ALA4431915 | F | Neuroprotective activity in Sprague-Dawley rat astrocytes assessed as [methyl-3H]thymidine incorporation at 10 to 50 uM after 8 days by liquid scintillation counting assay relative to control | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
7. | ALA4604132 | F | Neuroprotective activity against amyloid-beta42-induced cell death in astrocytes isolated from cortex of Sprague-Dawley rat assessed as decrease in cell viability at 5 to 100 uM pretreated for 2 hrs followed by amyloid-beta42 stimulation measured after 24 hrs by MTT assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
8. | ALA4767682 | A | Cytotoxicity against Wistar rat astrocytes assessed as cell growth inhibition measured after 72 hrs by SRB assay | Rattus norvegicus | 18 | cell-based format | Scientific Literature | ||
9. | ALA4767711 | A | Cytotoxicity against Wistar rat astrocytes assessed as cell growth inhibition at 100 uM measured after 72 hrs by SRB assay | Rattus norvegicus | 22 | cell-based format | Scientific Literature |