# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1013776 | F | Immunosuppressive activity in human B cell assessed as inhibition of mitogenesis | Homo sapiens | 1 | ALA1137794 | cell-based format | Scientific Literature | |
2. | ALA1838282 | F | Immunomodulatory activity in human primary B cells assessed as induction of CD69 expression after 24 hrs by FITC-conjugated flow cytometry | Homo sapiens | 21 | ALA1833860 | cell-based format | Scientific Literature | |
3. | ALA3385737 | F | Immunosuppressive activity in CPG oligonucleotide-induced human B cells assessed as inhibition of IgG production by immune assay | Homo sapiens | 6 | ALA3351657 | cell-based format | Scientific Literature | |
4. | ALA4195791 | F | Inhibition of BAFF-stimulated human peripheral blood B cell survival preincubated for 1 hr followed by BAFF stimulation measured after 4 days by Cell-Titer Glo assay | Homo sapiens | 1 | ALA4190405 | cell-based format | Scientific Literature | |
5. | ALA4219809 | A | Antiproliferative activity against human primary B cells | Homo sapiens | 1 | ALA4219038 | cell-based format | Scientific Literature | |
6. | ALA4235799 | A | Cytotoxicity against human B cells assessed as ATP content at 30 uM by cell titer glo-based luminescence assay relative to control | Homo sapiens | 2 | ALA4229521 | cell-based format | Scientific Literature | |
7. | ALA4351088 | F | Cytotoxicity against human B cells | Homo sapiens | 1 | ALA4350952 | cell-based format | Scientific Literature | |
8. | ALA4390024 | F | Antiproliferative activity against goat anti-human IgM antibody/recombinant human IL4-stimulated human PBMC-derived B cells assessed as decrease in cell viability pretreated for 30 mins followed by goat anti-human IgM antibody/recombinant human IL4 stimulation for 3 days by CellTiter-Glo reagent assay | Homo sapiens | 2 | ALA4387741 | cell-based format | Scientific Literature | |
9. | ALA4390025 | F | Antiproliferative activity against goat anti-human IgM antibody-stimulated human PBMC-derived B cells assessed as decrease in cell viability pretreated for 30 mins followed by goat anti-human IgM antibody stimulation for 3 days by CellTiter-Glo reagent assay | Homo sapiens | 2 | ALA4387741 | cell-based format | Scientific Literature | |
10. | ALA4390026 | F | Antiproliferative activity against goat anti-human IgM antibody/BAFF-stimulated human PBMC-derived B cells assessed as decrease in cell viability pretreated for 30 mins followed by goat anti-human IgM antibody/BAFF stimulation for 3 days by CellTiter-Glo reagent assay | Homo sapiens | 2 | ALA4387741 | cell-based format | Scientific Literature | |
11. | ALA4414014 | A | Cytotoxicity against human B cells assessed as cell death after 48 hrs by annexin V/propidium iodide-staining based flow cytometry | Homo sapiens | 7 | ALA4411330 | cell-based format | Scientific Literature | |
12. | ALA4427874 | F | Antiproliferative activity against human B cells by thymidine incorporation assay | Homo sapiens | 10 | ALA4425186 | cell-based format | Scientific Literature | |
13. | ALA4427927 | F | Immunostimulatory activity in CFSE-labeled human B cells assessed as TLR7 agonist-induced cell proliferation after 6 days by FACS analysis | Homo sapiens | 11 | ALA4425188 | cell-based format | Scientific Literature | |
14. | ALA4428712 | F | Inhibition of cell proliferation of human B cells pre-incubated for 30 mins before anti-IgM/CD40L stimulation and measured after 72 hrs by [3H]thymidine incorporation assay | Homo sapiens | 17 | ALA4428047 | cell-based format | Scientific Literature | |
15. | ALA4616772 | A | Cytotoxicity against human peripheral B cells assessed as reduction in cell viability | Homo sapiens | 1 | ALA4616583 | cell-based format | Scientific Literature | |
16. | ALA4672870 | F | Antiproliferative activity against anti-IgM/IgG-induced human peripheral B cells | Homo sapiens | 2 | ALA4665894 | cell-based format | Scientific Literature | |
17. | ALA4723702 | A | Cytotoxicity against human naive B cells assessed as reduction in cll viability at 10 uM after 48 hrs by PrestoBlue cell viability assay | Homo sapiens | 1 | ALA4715865 | cell-based format | Scientific Literature | |
18. | ALA4723704 | A | Cytotoxicity against human naive B cells assessed as reduction in cll viability at 25 to 50 uM after 48 hrs by PrestoBlue cell viability assay | Homo sapiens | 2 | ALA4715865 | cell-based format | Scientific Literature | |
19. | ALA5039758 | F | Immunostimulatory activity in human B cells assessed as fold increase at 0.1 to 10 uM incubated for 48 hrs by flow cytometry analysis | Homo sapiens | 1 | ALA5038589 | cell-based format | Scientific Literature | |
20. | ALA5051229 | F | Induction of anti-IgM-stimulated human CD20+ B cell activation at 10 to 1000 uM assessed as increase in CD69 expression measured as mean fluorescence intensity AUC by flow cytometry analysis | Homo sapiens | 33 | ALA5050844 | cell-based format | Patent Bioactivity Data |