# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA912708 | F | Protective effect against L-glutamate-induced neurotoxicity in rat primary cortical neurons at 10 uM by trypan blue exclusion method | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
2. | ALA912709 | F | Protective effect against L-glutamate-induced neurotoxicity in rat primary cortical neurons at 1 uM by trypan blue exclusion method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
3. | ALA2025122 | F | Neuroprotective activity in rat cortical neurons assessed as decrease in LPS-induced nitrite production at 28 to 52 ug/ml after 24 hrs administered 1 hr before LPS challenge by Griess method | Rattus norvegicus | 5 | assay format | Scientific Literature | ||
4. | ALA2067005 | F | Neuroprotective activity against Wistar rat Cortical neurons assessed as reduction of oxygen-glucose-deprivation-induced ROS production at 1 uM treated during reperfusion measured after 24 hrs by H2DCF-DA assay | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
5. | ALA2067006 | F | Neuroprotective activity against Wistar rat Cortical neurons assessed as reduction of oxygen-glucose-deprivation-induced lipid peroxidation at 1 uM treated during reperfusion measured after 24 hrs by TBARS method | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
6. | ALA2067007 | F | Neuroprotective activity against Wistar rat Cortical neurons assessed as reduction of oxygen-glucose-deprivation-induced lipid peroxidation at 100 uM treated during reperfusion measured after 24 hrs by TBARS method | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
7. | ALA2067008 | F | Neuroprotective activity against Wistar rat Cortical neurons assessed as reduction of oxygen-glucose-deprivation-induced LDH release at 1 to 100 uM treated during reperfusion measured after 24 hrs | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
8. | ALA2067009 | F | Neuroprotective activity against Wistar rat Cortical neurons assessed as reduction of oxygen-glucose-deprivation-induced caspase-3 activity at 1 to 100 uM treated during reperfusion measured after 24 hrs by spectrofluorometer analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
9. | ALA2067010 | F | Neuroprotective activity against Wistar rat Cortical neurons assessed as reduction of oxygen-glucose-deprivation-induced mitochondrial membrane potential at 1 to 100 uM treated during reperfusion measured after 24 hrs by spectrofluorometer analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
10. | ALA902650 | F | Induction of neurite outgrowth in Long-Evans rat E18/19 cortical neurons after 72 hrs | Rattus norvegicus | 91 | assay format | Scientific Literature | ||
11. | ALA897393 | F | Inhibition of beta-amyloid (1-42)-induced toxicity in embryonic rat brain primary cortical neurons after 48 hrs | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
12. | ALA897394 | F | Inhibition of beta-amyloid (25-35)-induced toxicity in embryonic rat brain primary cortical neurons after 48 hrs | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
13. | ALA2020243 | F | Increase in BDNF eIV-IX mRNA expression in rat cortical neurons at 1 uM after 3 hrs by RT-PCR analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
14. | ALA2020244 | F | Increase in BDNF eIV-IX mRNA expression in rat cortical neurons at 10 uM after 3 hrs by RT-PCR analysis | Rattus norvegicus | 8 | assay format | Scientific Literature | ||
15. | ALA2020245 | F | Increase in BDNF eIV-IX mRNA expression in rat cortical neurons at 10 uM after 3 hrs by RT-PCR analysis in presence of VSSC antagonist TTX | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
16. | ALA2020246 | F | Increase in BDNF eIV-IX mRNA expression in rat cortical neurons at 10 uM after 3 hrs by RT-PCR analysis in presence of L-type voltage calcium channel blocker nicradipine | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
17. | ALA2020247 | F | Increase in BDNF eIV-IX mRNA expression in rat cortical neurons at 10 uM after 3 hrs by RT-PCR analysis in presence of ERK1/2 inhibitor U0126 | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
18. | ALA2020248 | F | Increase in BDNF eIV-IX mRNA expression in rat cortical neurons after 3 hrs by RT-PCR analysis | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
19. | ALA2020310 | F | Increase in neurite crossings in rat cortical neurons at 1 uM after 6 hrs by Sholl analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
20. | ALA2020311 | F | Increase in neurite length in rat cortical neurons at 1 uM after 6 hrs by anti-GFP and anti-MAP2-based fluorescence microscopy | Rattus norvegicus | 1 | assay format | Scientific Literature |