# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4133746 | A | Cytotoxicity against human epidermal keratinocytes assessed as decrease in cell viability at 128 ug/ml after 24 hrs by Alamar blue assay | Homo sapiens | 4 | ALA4130441 | assay format | Scientific Literature | |
2. | ALA4253037 | A | Cytotoxicity against human epidermal keratinocytes assessed as cell viability at 11 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA4251585 | assay format | Scientific Literature | |
3. | ALA4256162 | A | Cytotoxicity against human epidermal keratinocytes after 24 hrs by alamar blue assay | Homo sapiens | 1 | ALA4251718 | assay format | Scientific Literature | |
4. | ALA4385242 | A | Cytotoxicity against human keratinocytes after 48 hrs by XTT assay | Homo sapiens | 1 | ALA4382274 | cell-based format | Scientific Literature | |
5. | ALA4388490 | A | Induction of irritation in human epidermal keratinocytes assessed as effect on cell viability over 24 hrs | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
6. | ALA4388500 | A | Induction of irritation in human epidermal keratinocytes assessed as effect on IL1alpha levels over 24 hrs | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
7. | ALA4430244 | A | Cytotoxicity against human keratinocytes assessed as cell viability at 5 uM after 48 hrs by trypan blue exclusion assay relative to control | Homo sapiens | 1 | ALA4428084 | cell-based format | Scientific Literature | |
8. | ALA4430246 | A | Cytotoxicity against human keratinocytes assessed as cell viability at 10 uM after 48 hrs by trypan blue exclusion assay relative to control | Homo sapiens | 1 | ALA4428084 | cell-based format | Scientific Literature | |
9. | ALA4604581 | A | Cytotoxicity against human Keratinocytes assessed as reduction in cell viability at 4 uM incubated up to 72 hrs by CellTiter-Glo assay | Homo sapiens | 1 | ALA4602675 | cell-based format | Scientific Literature | |
10. | ALA4604582 | A | Cytotoxicity against human Keratinocytes assessed as reduction in cell viability 2 to 4 uM incubated up to 72 hrs by CellTiter-Glo assay | Homo sapiens | 1 | ALA4602675 | cell-based format | Scientific Literature | |
11. | ALA4622211 | A | Phototoxicity in human Keratinocytes in presence of UVA at 320 to 400 nm | Homo sapiens | 6 | ALA4619803 | cell-based format | Scientific Literature | |
12. | ALA4622214 | T | Dark toxicity in human Keratinocytes assessed as reduction in cell viability | Homo sapiens | 1 | ALA4619803 | cell-based format | Scientific Literature | |
13. | ALA4622215 | A | Ratio of IC50 for dark toxicity in human Keratinocytes to IC50 for phototoxicity in human Keratinocytes in presence of UVA at 320 to 400 nm | Homo sapiens | 3 | ALA4619803 | cell-based format | Scientific Literature | |
14. | ALA4814844 | A | Cytotoxicity against human epidermal keratinocytes assessed as reduction in cell viability measured after 24 hrs by Alamar blue assay | Homo sapiens | 4 | ALA4813926 | cell-based format | Scientific Literature | |
15. | ALA4836748 | A | Cytotoxicity against human Keratinocytes assessed as reduction in cell viability at 10 to 100 uM after 24 hrs by MTT assay | Homo sapiens | 1 | ALA4834471 | cell-based format | Scientific Literature | |
16. | ALA4836749 | F | Antiinflammatory activity in cytokine cocktail-induced reconstructed human epidermis model assessed as reduction in IL-8 level at 5 to 25 uM after 4 days by ELISA | Homo sapiens | 1 | ALA4834471 | cell-based format | Scientific Literature | |
17. | ALA4836750 | F | Antiinflammatory activity in cytokine cocktail-induced reconstructed human epidermis model assessed as attenuation of epidermal disorganization at 5 to 25 uM after 4 days by HE staining based assay | Homo sapiens | 1 | ALA4834471 | cell-based format | Scientific Literature | |
18. | ALA4836751 | F | Antiinflammatory activity in cytokine cocktail-induced reconstructed human epidermis model assessed as improved skin barrier functions at 5 to 25 uM after 4 days | Homo sapiens | 1 | ALA4834471 | cell-based format | Scientific Literature | |
19. | ALA4836752 | F | Antiinflammatory activity in cytokine cocktail-induced reconstructed human epidermis model assessed as decrease in pH at 5 to 25 uM after 4 days | Homo sapiens | 1 | ALA4834471 | cell-based format | Scientific Literature | |
20. | ALA4836753 | F | Antiinflammatory activity in cytokine cocktail-induced reconstructed human epidermis model assessed as effect on TSLP expression at 5 to 25 uM after 4 days by ELISA | Homo sapiens | 1 | ALA4834471 | cell-based format | Scientific Literature |