| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3874799 | F | Inhibition of LPS-stimulated nitric oxide production in ddy mouse peritoneal macrophages measured after 20 hrs by Greiss method | Mus musculus | 12 | ALA3872265 | assay format | Scientific Literature | |
| 2. | ALA3878053 | F | Anti-inflammatory activity in mouse peritoneal macrophage assessed as inhibition of LPS-induced IL-6 expression at 10 uM pretreated for 30 mins followed by LPS challenge measured after 6 hrs by q-PCR analysis | Mus musculus | 1 | ALA3877268 | assay format | Scientific Literature | |
| 3. | ALA3878054 | F | Anti-inflammatory activity in mouse peritoneal macrophage assessed as inhibition of LPS-induced IL-12 mRNA expression at 10 uM pretreated for 30 mins followed by LPS challenge measured after 6 hrs by q-PCR analysis | Mus musculus | 1 | ALA3877268 | assay format | Scientific Literature | |
| 4. | ALA3878055 | F | Anti-inflammatory activity in mouse peritoneal macrophage assessed as inhibition of LPS-induced IL-33 mRNA expression at 10 uM pretreated for 30 mins followed by LPS challenge measured after 6 hrs by q-PCR analysis | Mus musculus | 1 | ALA3877268 | assay format | Scientific Literature | |
| 5. | ALA3878056 | F | Anti-inflammatory activity in mouse peritoneal macrophage assessed as inhibition of LPS-induced TNF-alpha mRNA expression at 10 uM pretreated for 30 mins followed by LPS challenge measured after 6 hrs by q-PCR analysis | Mus musculus | 1 | ALA3877268 | assay format | Scientific Literature | |
| 6. | ALA4004985 | F | Inhibition of LPS-stimulated TNFalpha secretion in C57BL6J mouse peritoneal macrophages at 50 uM after 24 hrs | Mus musculus | 1 | ALA4004792 | cell-based format | Scientific Literature | |
| 7. | ALA4034905 | A | Cytotoxicity against mouse peritoneal macrophages after 72 hrs by MTT assay | Mus musculus | 4 | ALA4033653 | cell-based format | Scientific Literature | |
| 8. | ALA4042109 | A | Cytotoxicity against Balb/c mouse peritoneal macrophages assessed as reduction in cell viability after 48 hrs by MTT assay | Mus musculus | 41 | ALA4041500 | cell-based format | Scientific Literature | |
| 9. | ALA4043007 | F | Anti-inflammatory activity in C57BL/6 mouse primary peritoneal macrophages assessed as inhibition of LPS-induced IL-6 production by ELISA method | Mus musculus | 1 | ALA4041549 | cell-based format | Scientific Literature | |
| 10. | ALA4043008 | F | Anti-inflammatory activity in C57BL/6 mouse primary peritoneal macrophages assessed as inhibition of LPS-induced TNF-alpha production by ELISA method | Mus musculus | 1 | ALA4041549 | cell-based format | Scientific Literature | |
| 11. | ALA4132669 | A | Cytotoxicity against BALB/c mouse peritoneal macrophages assessed as reduction in cell viability after 48 hrs by MTT assay | Mus musculus | 3 | ALA4130385 | cell-based format | Scientific Literature | |
| 12. | ALA4132671 | A | Cytotoxicity against BALB/c mouse peritoneal macrophages assessed as reduction in cell viability at 10'-4 M after 48 hrs by MTT assay relative to control | Mus musculus | 1 | ALA4130385 | cell-based format | Scientific Literature | |
| 13. | ALA4132672 | A | Cytotoxicity against BALB/c mouse peritoneal macrophages assessed as reduction in cell viability at 5 x 10'-4 M after 48 hrs by MTT assay relative to control | Mus musculus | 1 | ALA4130385 | cell-based format | Scientific Literature | |
| 14. | ALA4132796 | A | Cytotoxicity against BALB/c mouse peritoneal macrophages after 48 hrs by MTT assay | Mus musculus | 40 | ALA4130392 | cell-based format | Scientific Literature | |
| 15. | ALA4132799 | F | Induction of NO generation in Leishmania donovani MHOM/IN/AG/83 infected BALB/c mouse peritoneal macrophages assessed as nitrite levels after 48 hrs by Griess assay relative to untreated control | Mus musculus | 40 | ALA4130392 | cell-based format | Scientific Literature | |
| 16. | ALA4132802 | F | Induction of innate immune response in Leishmania donovani MHOM/IN/AG/83 infected BALB/c mouse peritoneal macrophages assessed as increase in iNOS2 mRNA expression at 2.5 ug/ml incubated for 6 hrs by RT-PCR analysis relative to control | Mus musculus | 1 | ALA4130392 | cell-based format | Scientific Literature | |
| 17. | ALA4132803 | F | Induction of innate immune response in Leishmania donovani MHOM/IN/AG/83 infected BALB/c mouse peritoneal macrophages assessed as reduction in arginase 1 activity at 1 to 5 ug/ml incubated for 48 hrs using L-arginine and by spectrometry relative to control | Mus musculus | 1 | ALA4130392 | cell-based format | Scientific Literature | |
| 18. | ALA4132804 | F | Induction of innate immune response in Leishmania donovani MHOM/IN/AG/83 infected BALB/c mouse peritoneal macrophages assessed as upregulation of IL-12 levels at 2.5 ug/ml after 24 hrs by sandwich ELISA | Mus musculus | 1 | ALA4130392 | cell-based format | Scientific Literature | |
| 19. | ALA4132805 | F | Induction of innate immune response in Leishmania donovani MHOM/IN/AG/83 infected BALB/c mouse peritoneal macrophage assessed as downregulation of IL-10 levels at 2.5 ug/ml after 24 hrs by sandwich ELISA | Mus musculus | 1 | ALA4130392 | cell-based format | Scientific Literature | |
| 20. | ALA4132806 | F | Induction of innate immune response in Leishmania donovani MHOM/IN/AG/83 infected BALB/c mouse peritoneal macrophages assessed as upregulation of IL-12 mRNA expression at 2.5 ug/ml after 6 hrs by RT-PCR analysis | Mus musculus | 1 | ALA4130392 | cell-based format | Scientific Literature |
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