| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA656658 | B | Percent degraded by the cathepsin B after incubation for 4 hrs was determined by HPLC | 19 | single protein format | Scientific Literature | |||
| 2. | ALA656659 | B | Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester as substrate | 15 | single protein format | Scientific Literature | |||
| 3. | ALA656660 | B | Inhibition of cathepsin B with Cbz-L-lysine-p-nitrophenyl ester; Not significantly active | Bos taurus | 1 | single protein format | Scientific Literature | ||
| 4. | ALA876944 | B | Tested for the ability to inhibit bovine liver cathepsin B at 0.5 mM | 1 | assay format | Scientific Literature | |||
| 5. | ALA656661 | B | Proteolysis rate constant (Kcat), when mixed with Cathepsin B enzyme for the conversion of water-soluble compound to fluorescent oil-soluble compound | 1 | single protein format | Scientific Literature | |||
| 6. | ALA658481 | B | Ability to block cathepsin B-catalyzed hydrolysis of the fluorogenic substrate Z-Arg-Arg-NHMec | 4 | single protein format | Scientific Literature | |||
| 7. | ALA659000 | B | Inhibition of bovine cathepsin B | 45 | single protein format | Scientific Literature | |||
| 8. | ALA659001 | B | Inhibition of alpha-keto esters towards cathepsin B at pH 5.2 | 51 | single protein format | Scientific Literature | |||
| 9. | ALA872428 | B | Tested for inhibitory activity against bovine cathepsin B. | 1 | single protein format | Scientific Literature | |||
| 10. | ALA875687 | B | Proteolysis constant (Km), when mixed with Cathepsin B enzyme for the conversion of water-soluble compound to fluorescent oil-soluble compound | 1 | single protein format | Scientific Literature | |||
| 11. | ALA659002 | B | Rate of cathepsin B inactivation in vitro in bovine spleen | 10 | tissue-based format | Scientific Literature | |||
| 12. | ALA659003 | B | The apparent second-order rate constant for inactivation of bovine cathepsin B enzyme. Apparent rate constant was determined from repeats of Kobs vs [I] using at least 5 values of [I]. | 7 | single protein format | Scientific Literature | |||
| 13. | ALA659004 | B | Specificity constant is determined from the ratio of the inactivation rate constants (Kcat/Km)of the cathepsin B. | 7 | single protein format | Scientific Literature | |||
| 14. | ALA659972 | B | Second-order rate constant for the inactivation of mammalian lysosomal cathepsin B. | 1 | single protein format | Scientific Literature | |||
| 15. | ALA659973 | B | Second-order rate constants for the inactivation of mammalian lysosomal cathepsin B at pH 6.5 | 1 | single protein format | Scientific Literature | |||
| 16. | ALA659974 | B | Second-order rate constants for the inactivation of mammalian lysosomal cathepsin B at pH=6.5 | 1 | single protein format | Scientific Literature | |||
| 17. | ALA659975 | B | Evaluated for second-order rate constants for the inactivation of mammalian lysosomal cathepsin B. | 19 | single protein format | Scientific Literature | |||
| 18. | ALA659976 | B | Second-order rate constants for the inactivation of mammalian lysosomal cathepsin B; no inhibition | 1 | single protein format | Scientific Literature | |||
| 19. | ALA659977 | B | Compound was evaluated for the ability to inhibit cathepsin B purified from bovine spleen | 3 | tissue-based format | Scientific Literature | |||
| 20. | ALA659978 | B | Compound was evaluated for the ability to inhibit cathepsin B purified from bovine spleen; ND=Not determined | 1 | tissue-based format | Scientific Literature |
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