# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3880969 | B | Inhibition of ACAT2 in mouse hepatic microsomal membranes assessed as decrease in formation of [14C]cholesteryl oleate from [1,14C]oleoyl co-enzyme A after 5 mins by bio-image analyzer | Mus musculus | 35 | ALA3880418 | cell membrane format | Patent Bioactivity Data | |
2. | ALA3880970 | B | Ratio of compound IC50 to PRD 043 IC50 for ACAT2 in mouse hepatic microsomal membranes | Mus musculus | 35 | ALA3880418 | cell membrane format | Patent Bioactivity Data | |
3. | ALA4418324 | B | Inhibition of ACAT2 in mouse hepatic microsome membranes using [1-14C]oleoyl coenzyme A as substrate incubated for 5 mins | Mus musculus | 35 | ALA4418261 | microsome format | Patent Bioactivity Data | |
4. | ALA4418325 | B | Potency index, ratio of PRD-043 IC50 to test compound IC50 for inhibition ACAT2 in mouse hepatic microsome membranes using [1-14C]oleoyl coenzyme A as substrate incubated for 5 mins | Mus musculus | 35 | ALA4418261 | microsome format | Patent Bioactivity Data |