# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615228 | Functional | Evaluated for inhibition of bovine adrenal cortical mitochondrial 11 beta-hydroxylase | Bos taurus | 15 | ALA1122743 | assay format | Scientific Literature | |
2. | ALA665986 | Binding | Inhibition of Corticoid 11-beta-hydroxylase cytochrome P450 | Bos taurus | 3 | ALA1125500 | single protein format | Scientific Literature | |
3. | ALA835491 | Binding | In vitro inhibition against bovine cytochrome P450 11B with 200 uM corticosterone | CYP11B | 17 | ALA1144350 | single protein format | Scientific Literature | |
4. | ALA835567 | Binding | In vitro inhibition against bovine cytochrome P450 11B with 200 uM corticosterone; nd= not determined | CYP11B | 1 | ALA1144350 | single protein format | Scientific Literature | |
5. | ALA1908238 | ADME | Mechanism based inhibition of bovine cytochrome P450 CYP11B1 | Bos taurus | 1 | ALA1743341 | single protein format | Scientific Literature | |
6. | ALA3256606 | Binding | Inhibition of bovine adrenal gland 11beta-hydroxylase assessed as inhibition of [14C]-deoxycorticosterone hydroxylation at 2 uM | Bos taurus | 14 | ALA3243950 | single protein format | Scientific Literature | |
7. | ALA3256607 | Binding | Inhibition of bovine adrenal gland 11beta-hydroxylase assessed as inhibition of [14C]-deoxycorticosterone hydroxylation at 2 uM relative to metyrapone | Bos taurus | 14 | ALA3243950 | single protein format | Scientific Literature | |
8. | ALA3256608 | Binding | Inhibition of bovine adrenal gland 11beta-hydroxylase assessed as inhibition of [14C]-deoxycorticosterone hydroxylation | Bos taurus | 1 | ALA3243950 | single protein format | Scientific Literature | |
9. | ALA3256609 | Binding | Inhibition of bovine adrenal gland 11beta-hydroxylase assessed as amount of corticosterone production using 22 nmol [14C]-deoxycorticosterone measured per 5 mins at 2 nmol (Rvb = 1.3 +/- 0.04 nmol) | Bos taurus | 1 | ALA3243950 | single protein format | Scientific Literature | |
10. | ALA3256610 | Binding | Inhibition of bovine adrenal gland 11beta-hydroxylase assessed as amount of corticosterone production using 22 nmol [14C]-deoxycorticosterone measured per 5 mins at 2 nmol | Bos taurus | 1 | ALA3243950 | single protein format | Scientific Literature | |
11. | ALA3256611 | Binding | Inhibition of bovine adrenal gland 11beta-hydroxylase assessed as amount of corticosterone production using 11 nmol [14C]-deoxycorticosterone measured per 5 mins at 2 nmol (Rvb = 1.3 +/- 0.04 nmol) | Bos taurus | 1 | ALA3243950 | single protein format | Scientific Literature | |
12. | ALA3256612 | Binding | Inhibition of bovine adrenal gland 11beta-hydroxylase assessed as amount of corticosterone production using 11 nmol [14C]-deoxycorticosterone measured per 5 mins at 2 nmol | Bos taurus | 1 | ALA3243950 | single protein format | Scientific Literature |