# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA666233 | Binding | Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in rat | 70 | ALA1129574 | assay format | Scientific Literature | ||
2. | ALA882940 | Binding | Inhibitory activity against rat dihydroorotate dehydrogenase | Rattus norvegicus | 4 | ALA1140402 | single protein format | Scientific Literature | |
3. | ALA884638 | Binding | Inhibitory activity against rat dihydroorotate dehydrogenase | Rattus norvegicus | 1 | ALA1140402 | single protein format | Scientific Literature | |
4. | ALA855444 | Functional | Antagonist activity against DHOD in rat | Rattus norvegicus | 1 | ALA1139219 | assay format | Scientific Literature | |
5. | ALA907887 | Binding | Inhibition of rat DHODH | Rattus norvegicus | 6 | ALA1139746 | single protein format | Scientific Literature | |
6. | ALA1948717 | Binding | Inhibition of dihydroorotate dehydrogenase in Wistar rat liver mitochondrial/microsomal membranes measured for 5 mins by 2,6-dichlorophenolindophenol reduction-based spectrophotometry | Rattus norvegicus | 14 | ALA1944517 | cell membrane format | Scientific Literature | |
7. | ALA1930746 | Binding | Inhibition of rat dihydroorotate dehydrogenase | Rattus norvegicus | 2 | ALA1926525 | single protein format | Scientific Literature | |
8. | ALA1663403 | Binding | Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assay | Rattus norvegicus | 6 | ALA1649376 | tissue-based format | Scientific Literature | |
9. | ALA1663404 | Binding | Inhibition of DHODH in Wistar rat liver homogenates at 100 uM by DCIP reduction assay | Rattus norvegicus | 24 | ALA1649376 | tissue-based format | Scientific Literature | |
10. | ALA2340287 | Binding | Inhibition of rat recombinant His-tagged truncated DHODH expressed in Escherichia coli using dihydroorotate as substrate by chromogen reduction assay | Rattus norvegicus | 1 | ALA2331175 | assay format | Scientific Literature | |
11. | ALA2340291 | Binding | Inhibition of rat purified recombinant DHODH | Rattus norvegicus | 2 | ALA2331175 | single protein format | Scientific Literature | |
12. | ALA2340293 | Binding | Competitive inhibition of rat purified recombinant DHODH in presence of cofactor ubiquinone | Rattus norvegicus | 1 | ALA2331175 | single protein format | Scientific Literature | |
13. | ALA3296348 | Binding | Inhibition of rat DHODH (amino acid residues 30 to 396) expressed in Escherichia coli BL21 cells assessed as orotic acid production using dihydroorotate as substrate by DCIP dye-based assay | Rattus norvegicus | 8 | ALA3286300 | cell-based format | Scientific Literature | |
14. | ALA3296351 | Binding | Binding affinity to rat DHODH by isothermal titration calorimetry | Rattus norvegicus | 4 | ALA3286300 | single protein format | Scientific Literature | |
15. | ALA4605397 | ADME | Inhibition of C-terminal His6-tagged rat DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assay | Rattus norvegicus | 8 | ALA4602703 | cell-based format | Scientific Literature | |
16. | ALA4706784 | Binding | Inhibition of N-terminal His6-tagged rat DHODH expressed in Escherichia coli BL21 expressed in Escherichia coli BL21 using L-DHO as substrate and CoQ as co-substrate by DCIP dye based spectrophotometric assay | Rattus norvegicus | 6 | ALA4706474 | assay format | Scientific Literature | |
17. | ALA4812661 | ADME | Inhibition of rat DHODH up to 100 uM | Rattus norvegicus | 5 | ALA4811258 | single protein format | Scientific Literature | |
18. | ALA5142004 | Binding | Inhibition of rat DHODH | Rattus norvegicus | 2 | ALA5137081 | single protein format | Scientific Literature |