| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA816522 | B | Inhibitory activity against cognate Staphylococcus aureus threonyl tRNA synthetase | Staphylococcus aureus | 1 | single protein format | Scientific Literature | ||
| 2. | ALA816523 | B | Inhibitory activity against cognate Staphylococcus aureus threonyl tRNA synthetase at 300 uM | Staphylococcus aureus | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2317882 | B | Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometry | Homo sapiens | 24 | single protein format | Scientific Literature | ||
| 4. | ALA3756434 | B | Inhibition of ThRS in human UMSCC1 cells assessed as increase in CHOP mRNA level at 5 uM after 6 hrs by RT-qPCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA3756435 | B | Inhibition of ThRS in human UMSCC1 cells assessed as increase in ATF3 mRNA level at 5 uM after 6 hrs by RT-qPCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA3757444 | B | Inhibition of ThRS in human UMSCC1 cells assessed as increase in ATF4 mRNA level at 5 uM after 6 hrs by RT-qPCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA3757446 | B | Inhibition of ThRS in human UMSCC1 cells assessed as increase in XBP1 splicing by RT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA3757450 | B | Inhibition of ThRS in human UMSCC1 cells assessed as increase in caspase-3/7 level at 5 uM after 4 hrs by luminescent assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3757451 | B | Inhibition of ThRS in human UMSCC1 cells assessed as increase in UPR-related gene expression at 10 uM by RT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA3757452 | B | Inhibition of ThRS in human UMSCC1 cells assessed as increase in DNA damaging-related gene expression at 10 uM by RT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA3757453 | B | Inhibition of ThRS in human UMSCC1 cells assessed as increase in apoptosis-related gene expression at 10 uM by RT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA3757454 | B | Inhibition of ThRS in human UMSCC14A cells assessed as increase in CHOP mRNA level at 5 uM after 6 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3757455 | B | Inhibition of ThRS in human UMSCC23 cells assessed as increase in CHOP mRNA level at 5 uM after 6 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3757456 | B | Inhibition of ThRS in human A253 cells assessed as increase in CHOP mRNA level at 5 uM after 6 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3757457 | B | Inhibition of ThRS in human UMSCC14A cells assessed as increase in XBP1 splicing by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3757458 | B | Inhibition of ThRS in human UMSCC23 cells assessed as increase in XBP1 splicing by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3757459 | B | Inhibition of ThRS in human A253 cells assessed as increase in XBP1 splicing by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3757460 | B | Inhibition of ThRS in human UMSCC14A cells assessed as increase in ATF3 mRNA level at 5 uM after 6 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3757461 | B | Inhibition of ThRS in human UMSCC23 cells assessed as increase in ATF3 mRNA level at 5 uM after 6 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3757462 | B | Inhibition of ThRS in human A253 cells assessed as increase in ATF3 mRNA level at 5 uM after 6 hrs by RT-qPCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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