# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3620959 | Functional | Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assay | Rattus norvegicus | 79 | ALA3616441 | cell-based format | Scientific Literature | |
2. | ALA3620960 | Binding | Negative allosteric modulation of rat mGlu3 receptor assessed as amplitude response at 30 uM relative to glutamate | Rattus norvegicus | 79 | ALA3616441 | single protein format | Scientific Literature | |
3. | ALA3619183 | Binding | Negative allosteric modulation of rat mGlu3 receptor assessed as progressive fold-shift of glutamate concentration response curve | Rattus norvegicus | 1 | ALA3616441 | single protein format | Scientific Literature | |
4. | ALA3789015 | Binding | Agonist activity at rat mGlu3 receptor expressed in HEK293 cells by [35S]GTP-gamma binding assay | Rattus norvegicus | 8 | ALA3784960 | cell-based format | Scientific Literature | |
5. | ALA3791048 | Binding | Agonist activity at rat mGlu3 receptor by FRET based mGlu sensor assay | Rattus norvegicus | 7 | ALA3784960 | single protein format | Scientific Literature | |
6. | ALA3789948 | Binding | Activity at rat mGluR3 expressed in HEK293-GIRK cells assessed as effect on glutamate-induced response by thallium flux assay | Rattus norvegicus | 1 | ALA3784934 | cell-based format | Scientific Literature | |
7. | ALA681705 | Binding | Binding affinity against glutamate receptor was measured using radioligand [3H]-kainic acid binding assay | Rattus norvegicus | 1 | ALA1123413 | single protein format | Scientific Literature | |
8. | ALA681706 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 0.5 uM. | Rattus norvegicus | 2 | ALA1123302 | tissue-based format | Scientific Literature | |
9. | ALA681707 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 1.0 uM. | Rattus norvegicus | 2 | ALA1123302 | tissue-based format | Scientific Literature | |
10. | ALA681708 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 10.0 uM. | Rattus norvegicus | 2 | ALA1123302 | tissue-based format | Scientific Literature | |
11. | ALA681709 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 100 uM. | Rattus norvegicus | 1 | ALA1123529 | assay format | Scientific Literature | |
12. | ALA681710 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 10 uM. | Rattus norvegicus | 3 | ALA1123529 | tissue-based format | Scientific Literature | |
13. | ALA681711 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 10 uM. | Rattus norvegicus | 4 | ALA1123302 | tissue-based format | Scientific Literature | |
14. | ALA681712 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 20 uM. | Rattus norvegicus | 1 | ALA1123302 | tissue-based format | Scientific Literature | |
15. | ALA681713 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 21 uM. | Rattus norvegicus | 1 | ALA1123302 | tissue-based format | Scientific Literature | |
16. | ALA681714 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 25 uM. | Rattus norvegicus | 3 | ALA1123529 | tissue-based format | Scientific Literature | |
17. | ALA681715 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 25 uM. | Rattus norvegicus | 2 | ALA1123302 | tissue-based format | Scientific Literature | |
18. | ALA681716 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 36 uM. | Rattus norvegicus | 1 | ALA1123529 | tissue-based format | Scientific Literature | |
19. | ALA681717 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 5.0 uM. | Rattus norvegicus | 2 | ALA1123302 | tissue-based format | Scientific Literature | |
20. | ALA681718 | Functional | Antagonistic activity against Glutamate receptor in rat spinal cord at concentration of 50.0 uM. | Rattus norvegicus | 1 | ALA1123302 | tissue-based format | Scientific Literature |