| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA653842 | B | Percent activity against CFTR (cystic fibrosis transmembrane conductance regulator) in rat relative to UCCF-152(50 uM) | 27 | assay format | Scientific Literature | |||
| 2. | ALA653843 | B | Kd (half effective concentration) of compound against CFTR (cystic fibrosis transmembrane conductance regulator) in rat was determined | 22 | assay format | Scientific Literature | |||
| 3. | ALA653844 | B | Vmax (maximal I influx) of compound against CFTR (cystic fibrosis transmembrane conductance regulator) in rat was determined | 18 | assay format | Scientific Literature | |||
| 4. | ALA4674764 | B | Induction of CFTR channel function restoration in FRT cells assessed as effect on forskolin induced transepithelial CFTR-mediated Cl- current by measuring basal short circuit current at 12 uM measured after 24 hrs by voltage clamp method | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA5231447 | B | Potentiation of CFTR F508del mutant in rat FRT cells assessed as increase in iodide influx in presence of forskolin | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5231448 | B | Potency index, ratio of genistein EC50 to test compound EC50 for potentiation of CFTR F508del mutant in rat FRT cells assessed as increase in iodide influx in presence of forskolin | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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