# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3606826 | Binding | Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes by liquid scintillation counting method | Mus musculus | 5 | ALA3603739 | cell membrane format | Scientific Literature | |
2. | ALA3614311 | Binding | Displacement of [3H]-DAMGO from Swiss Webster mouse neural membranes mu opioid receptor after 60 mins by liquid scintillation spectrometric analysis | Mus musculus | 1 | ALA3611974 | assay format | Scientific Literature | |
3. | ALA716078 | Functional | Compound was tested for its ability to antagonize the antinociceptive effect of morphine (mu opioid receptor agonist) in mice | Mus musculus | 4 | ALA1130045 | assay format | Scientific Literature | |
4. | ALA824003 | Functional | Tested for the antagonism of kappa diuresis at a dose of 0.08 mg/kg subcutaneously; Not active | 1 | ALA1126828 | organism-based format | Scientific Literature | ||
5. | ALA842494 | Functional | Antagonistic activity towards morphine induced mu-opioid receptor by mouse writhing assay at 1.25 mg/kg subcutaneously | 33 | ALA1127053 | organism-based format | Scientific Literature | ||
6. | ALA842495 | Functional | Antagonist selectivity of mu opioid receptor in treated mice at subcutaneous dose of 0.53 umol/kg at 30 min peak time by mouse tail-flick assay | 1 | ALA1127305 | tissue-based format | Scientific Literature | ||
7. | ALA842496 | Functional | Antagonist selectivity of mu opioid receptor in treated mice to that of control at subcutaneous dose of 16 umol/kg, morphine was injected subcutaneously, at 30 min peak time by Mouse tail-flick assay | 1 | ALA1127305 | tissue-based format | Scientific Literature | ||
8. | ALA842497 | Functional | Antagonist potency of compound was evaluated towards mu receptor in presence of agonist DPDPE by using Mouse Tail-Flick Assay | 1 | ALA1127843 | tissue-based format | Scientific Literature | ||
9. | ALA843460 | Functional | Antagonism of opioid analgesia using a mouse writhing model to block morphine (2.5 mg/kg) induced mu-opioid receptor (subcutaneously dosed) | 42 | ALA1126828 | organism-based format | Scientific Literature | ||
10. | ALA843466 | Binding | Inhibitory concentration against mu-opioid receptor in mouse vas deferens | 3 | ALA1126907 | single protein format | Scientific Literature | ||
11. | ALA845683 | Functional | Irreversible antagonist activity at mouse vas deferens mu receptor against DADLE after 30 min at 200 nM | Mus musculus | 12 | ALA1122615 | tissue-based format | Scientific Literature | |
12. | ALA838700 | Binding | Binding affinity against mu opioid receptor in mouse hot plate test | Mus musculus | 65 | ALA1138013 | single protein format | Scientific Literature | |
13. | ALA838830 | Binding | Binding constant for Opioid receptor mu 1 in mouse | Mus musculus | 3 | ALA1142053 | organism-based format | Scientific Literature | |
14. | ALA829050 | Binding | Inhibition of DAMGO (Tyr-[D-Ala]-Gly-[NMe-Phe]-Gly-ol) binding to mouse brain mu opioid receptor | Mus musculus | 11 | ALA1143632 | assay format | Scientific Literature | |
15. | ALA829267 | Binding | Ratio of binding affinity against mu to that of delta opioid receptor | Mus musculus | 51 | ALA1138013 | single protein format | Scientific Literature | |
16. | ALA924967 | Functional | Agonist activity at mu opioid receptor in NMRI mouse vas deferens assessed as inhibition of electrically-stimulated muscle contraction | Mus musculus | 6 | ALA1140695 | tissue-based format | Scientific Literature | |
17. | ALA924968 | Functional | Antagonist activity at mu opioid receptor in NMRI mouse vas deferens assessed as effect on endomorphin 2-induced muscle contraction | Mus musculus | 1 | ALA1140695 | tissue-based format | Scientific Literature | |
18. | ALA924969 | Functional | Antagonist activity at mu opioid receptor in NMRI mouse vas deferens assessed as effect on DAMGO-induced muscle contraction | Mus musculus | 1 | ALA1140695 | tissue-based format | Scientific Literature | |
19. | ALA924970 | Functional | Antagonist activity at mu opioid receptor in NMRI mouse vas deferens assessed as effect on Tyr-(R)-spiro-Aba-Gly-Phe-NH2 induced muscle contraction | Mus musculus | 1 | ALA1140695 | tissue-based format | Scientific Literature | |
20. | ALA1105638 | Functional | Agonist activity at mu opioid receptor in Swiss albino mouse ileum assessed as inhibition of electrically-stimulated muscle contraction | Mus musculus | 5 | ALA1157769 | tissue-based format | Scientific Literature |