| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA716078 | F | Compound was tested for its ability to antagonize the antinociceptive effect of morphine (mu opioid receptor agonist) in mice | Mus musculus | 4 | assay format | Scientific Literature | ||
| 2. | ALA735758 | F | Tested for inhibition of amplification of electrically induced twitch in mouse vas deferens (MVD) | Mus musculus | 6 | tissue-based format | Scientific Literature | ||
| 3. | ALA747709 | F | Agonist selectivity for mu opioid receptor in the beta-funaltrexamine-treated mice Subcutaneous dose of 20.36 umol/kg of beta-FNA was administered | 2 | assay format | Scientific Literature | |||
| 4. | ALA747710 | F | Agonist selectivity for mu opioid receptor in the beta-funaltrexamine-treated mice subcutaneous dose of 20.36 umol/kg of beta-FNA was administered | 1 | assay format | Scientific Literature | |||
| 5. | ALA747711 | F | Tested for antagonist activity against mu opioid receptor in mouse vas deferens preparation by using DAMGO as antagonist | 2 | assay format | Scientific Literature | |||
| 6. | ALA747712 | B | Inhibition of [3H]DAMGO from mouse brain homogenate Mu opioid receptor | Mus musculus | 10 | assay format | Scientific Literature | ||
| 7. | ALA747713 | B | Evaluated for the binding affinity at mu receptor | 1 | single protein format | Scientific Literature | |||
| 8. | ALA747714 | F | Antagonist potency was determined using morphine in mu-opioid receptor by icv administration in mouse after 24 hr; ED50 ratio | 2 | organism-based format | Scientific Literature | |||
| 9. | ALA747715 | F | Antinociceptive activity at mu opioid receptor antagonist beta-funaltrexamine (beta-FNA) at the dose of 10 umiol/kg (sc) | 1 | organism-based format | Scientific Literature | |||
| 10. | ALA747862 | F | Antinociceptive activity at mu opioid receptor from beta-funaltrexamine (beta-FNA) at the dose of 10 umol/kg (sc) | 1 | organism-based format | Scientific Literature | |||
| 11. | ALA747863 | F | Ratio of ED50 of compound to mu opioid receptor antagonist beta-funaltrexamine (FMN) at 10.18 umol/kg administarted sc | 2 | assay format | Scientific Literature | |||
| 12. | ALA747864 | F | Agonist selectivity for mu opioid receptor in the beta-funaltrexamine-treated mice Subcutaneous dose of 20.36 umol/kg of beta-FNA was administered | Mus musculus | 1 | assay format | Scientific Literature | ||
| 13. | ALA878554 | F | Selectivity against mu receptor in the presence of 0.5 nmol icv SIOM | 1 | assay format | Scientific Literature | |||
| 14. | ALA872770 | B | Ability to displace tritium-labeled naloxone at opioid receptor, at 10 uM concentration | 1 | single protein format | Scientific Literature | |||
| 15. | ALA758858 | B | Binding affinity against opioid receptor | 2 | single protein format | Scientific Literature | |||
| 16. | ALA758859 | B | Binding affinity against opioid receptor by displacing radioligand [3H]DAMGO | 1 | single protein format | Scientific Literature | |||
| 17. | ALA758860 | B | Binding affinity against opioid receptor by displacing radioligand [3H]DPDPE | 1 | single protein format | Scientific Literature | |||
| 18. | ALA758861 | B | Binding affinity against opioid receptor by displacing radioligand [3HlU69,593 | 1 | single protein format | Scientific Literature | |||
| 19. | ALA758862 | B | Opioid binding affinity was evaluated using [3H]DAMGO as radioligand | 4 | single protein format | Scientific Literature | |||
| 20. | ALA756564 | B | Compound was evaluated for the inhibition of [3H]naloxone binding to mouse brain homogenate at 1 nM in the absence of sodium | 3 | tissue-based format | Scientific Literature |
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