| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA711714 | F | Activity tested at cloned rat Metabotropic glutamate receptor 5 expressed in Chinese Hamster Ovary (CHO) cells | 1 | cell-based format | Scientific Literature | |||
| 2. | ALA711715 | B | Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5 | 8 | single protein format | Scientific Literature | |||
| 3. | ALA711716 | B | Concentration for half maximal activation of metabotropic glutamate mGluR5a in rat | 4 | assay format | Scientific Literature | |||
| 4. | ALA711717 | B | Concentration for half maximal activation of metabotropic glutamate mGluR5b in rat | 3 | assay format | Scientific Literature | |||
| 5. | ALA711718 | B | Effect on Metabotropic glutamate receptor 5 | 4 | single protein format | Scientific Literature | |||
| 6. | ALA711719 | F | Metabotropic glutamate receptor 5 agonist activity as basal [3H]- IP formation in rat | Rattus norvegicus | 9 | assay format | Scientific Literature | ||
| 7. | ALA711720 | F | Metabotropic glutamate receptor 5 agonist activity for basal [3H]- IP formation in rat; Not tested | 2 | assay format | Scientific Literature | |||
| 8. | ALA879746 | F | Tested for the agonistic activity against Metabotropic glutamate receptor 5 | 2 | assay format | Scientific Literature | |||
| 9. | ALA709903 | F | Tested for the agonistic activity against Metabotropic glutamate receptor 5; Not active | 1 | assay format | Scientific Literature | |||
| 10. | ALA709904 | B | In vivo intraperitoneal effective dose for affinity at the Metabotropic glutamate receptor 5 was determined by occupancy assay | 1 | organism-based format | Scientific Literature | |||
| 11. | ALA709905 | F | In vivo intraperitoneal effective dose for affinity at the Metabotropic glutamate receptor 5 was determined by occupancy assay | 1 | organism-based format | Scientific Literature | |||
| 12. | ALA709906 | F | Antagonistic activity against Metabotropic glutamate receptor 5 was determined | 1 | assay format | Scientific Literature | |||
| 13. | ALA709907 | F | Antagonistic activity against Metabotropic glutamate receptor 5 was determined at 1 mM; NE = No significant effect observed | 2 | assay format | Scientific Literature | |||
| 14. | ALA709908 | B | Binding affinity towards mGlu5 receptors in rat brain membranes was evaluated | 2 | cell membrane format | Scientific Literature | |||
| 15. | ALA709909 | F | Tested for the agonistic activity against Metabotropic glutamate receptor 5 | 1 | assay format | Scientific Literature | |||
| 16. | ALA857622 | B | Tested for displacement of [3H]3-methoxy-5-(pyridin-2-ylethynyl) pyridine from Metabotropic glutamate receptor 5 in rat cortical membrane | 1 | cell membrane format | Scientific Literature | |||
| 17. | ALA709910 | B | Inhibitory constant against cloned rat Metabotropic glutamate receptor 5 expressed in Chinese Hamster Ovary (CHO) cells | 2 | cell-based format | Scientific Literature | |||
| 18. | ALA709911 | B | Tested for displacement of [3H]3-methoxy-5-(pyridin-2-ylethynyl) pyridine from Metabotropic glutamate receptor 5 in rat cortical membrane | 7 | cell membrane format | Scientific Literature | |||
| 19. | ALA709912 | B | The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 5 using established second messenger assay systems. | 7 | single protein format | Scientific Literature | |||
| 20. | ALA709913 | B | The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 5 using established second messenger assay systems.; ND is Not Determined. | 1 | single protein format | Scientific Literature |
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