# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA665711 | B | Inhibitory activity against COX-1 from rat peritoneal leukocytes, measured by PGE-2 produced (enzyme immunoassay) | 3 | ALA1128035 | assay format | Scientific Literature | ||
2. | ALA878765 | B | Inhibition of Prostaglandin G/H synthase 1 using whole cell assay | Rattus norvegicus | 12 | ALA1129001 | single protein format | Scientific Literature | |
3. | ALA764254 | B | In vitro inhibition of Prostaglandin G/H synthase 1 | 4 | ALA1129002 | single protein format | Scientific Literature | ||
4. | ALA764255 | B | In vitro inhibitory concentration against rat prostaglandin G/H synthase 1 | 25 | ALA1133804 | single protein format | Scientific Literature | ||
5. | ALA764256 | B | In vitro inhibitory concentration against rat Prostaglandin G/H synthase 1; nd= not determined | 1 | ALA1133804 | single protein format | Scientific Literature | ||
6. | ALA880614 | B | Concentration required to inhibit cyclooxygenase-1 in rat blood | Rattus norvegicus | 3 | ALA1141070 | assay format | Scientific Literature | |
7. | ALA881981 | B | Percent inhibition against cyclooxygenase-1 at 100 uM in rat blood | Rattus norvegicus | 28 | ALA1141070 | assay format | Scientific Literature | |
8. | ALA1932105 | B | Inhibition of COX-1 in rat leukocytes assessed as reduction in PGE2 production from arachidonic acid at 10 nM preincubated for 10 mins by EIA | Rattus norvegicus | 11 | ALA1926643 | cell-based format | Scientific Literature | |
9. | ALA2039050 | B | Inhibition of COX1 in rat whole blood assessed as decreased PGE2 production | Rattus norvegicus | 1 | ALA2034937 | tissue-based format | Scientific Literature | |
10. | ALA3269582 | B | Inhibition of rat seminal vesicle COX-1 using arachidonic acid as substrate assessed as reduction of PGG2 to PGH2 incubated for 1 min prior to substrate addition measured after 25 secs by chromogenic assay | Rattus norvegicus | 10 | ALA3259612 | single protein format | Scientific Literature | |
11. | ALA3614428 | B | Inhibition of rat seminal vesicles COX-1 using arachidonic acid as substrate at 50 ug/ml preincubated for 5 mins followed by substrate addition after 20 mins by competitive PGE2 EIA method | Rattus norvegicus | 13 | ALA3611976 | single protein format | Scientific Literature | |
12. | ALA4044802 | A | Inhibition of COX-1 in rat peritoneal macrophages assessed as reduction in [125I]-6-Keto-PGF1alpha production using arachidonic acid as substrate pretreated for 30 mins followed by substrate addition measured after 30 mins | Rattus norvegicus | 19 | ALA4043129 | assay format | Scientific Literature | |
13. | ALA4232355 | B | Inhibition of cyclooxygenase-1 in rat RBL-1 cells preincubated for 10 mins followed by [14C]arachidonic acid addition and measured after 5 mins by radioligand binding assay | Rattus norvegicus | 1 | ALA4229386 | cell-based format | Scientific Literature | |
14. | ALA5291868 | F | Compound was evaluated for inhibition of rat Ptgs1 in an in vitro cell free assay measured by fluorescence spectroscopy | 1,201 | ALA5291721 | assay format | Scientific Literature | ||
15. | ALA5291897 | F | Compound was evaluated for inhibition of rat Ptgs1 in an in vitro cell free assay measured by fluorescence spectroscopy | 25 | ALA5291721 | assay format | Scientific Literature |